Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer.
By E. Kapiteijn, C. Marijnen, I. D. Nagtegaal, H. Putter, W. Steup, T. Wiggers, H. Rutten, Lars Påhlman, B. Glimelius, J. V. Krieken and 2 more. New England Journal of Medicine, 2001
2,435 citations recorded by the source corpus.
Subfields: Oncology, Pathology and Forensic Medicine, Surgery
View Paper: https://www.semanticscholar.org/paper/55de584499ceb5d16bbf94c4c28ee7efa14af3d6
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In Pathology and Forensic Medicine
Citations in the corpus
- The TME Trial After a Median Follow-up of 6 Years: Increased Local Control But No Survival Benefit in Irradiated Patients With Resectable Rectal Carcinoma (2007, background): “84).(15) In this article, we report on the results of the TME trial after a median follow-up of 6 years with a focus on subgroup analyses.”
- Diagnostic accuracy of preoperative magnetic resonance imaging in predicting curative resection of rectal cancer: prospective observational study (2006, background): “8 Therefore, the optimal management of rectal cancer requires detailed preoperative planning that includes the assessment of the relation of tumour to the mesorectal fascia.”
- Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03. (2009, background): “7% at 5 years was greater than that reported in the Dutch Colorectal Cancer Group.(5) The rate of local recurrence at 2 years was reduced from 8.”
- Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer (2011, background): “Meta-analyses of RCTs conducted in Europe and the United States have shown that surveillance after curative surgical resection of colorectal cancer contributes to improving the resection rate of recurrent tumors and to improving the prognosis [70–74] (CQ-19).”
- Pathological response following long‐course neoadjuvant chemoradiotherapy for locally advanced rectal cancer (2005, background): “The major landmark trials which have proven a benefit from neoadjuvant radiotherapy have used the short-course regimen.(4,6) In general, the short-course regimen is offered to all patients, irrespective of disease stage, whereas the longcourse regimen is reserved for those with cancers that have inv”
- Operative Versus Nonoperative Treatment for Stage 0 Distal Rectal Cancer Following Chemoradiation Therapy: Long-term Results (2004, background): “The use of preoperative CRT therapy may result in significant lower recurrence rates when compared with surgery alone and TME with similar morbidity and mortality rates.(24,26) However, the number of patients irradiated may exceed by far the number of who will actually benefit from this treatment st”
- Circumferential Margin Involvement Is Still an Important Predictor of Local Recurrence in Rectal Carcinoma: Not One Millimeter but Two Millimeters Is the Limit (2002, background): “In a large randomized multicenter study in the Netherlands, it was shown that preoperative radiotherapy is also effective when TME surgery is used.(8) Determination of completeness of resection of the tumor relies on the assessment of resection margins by the pathologist.”
- A randomized trial of laparoscopic versus open surgery for rectal cancer. (2015, neutral): “(%) Complete 589 (84) 303 (88) Partially complete 58 (8) 19 (6) Incomplete 19 (3) 9 (3) Missing data 33 (5) 14 (4) Lymph nodes harvested Median no.”