Circumferential Margin Involvement Is Still an Important Predictor of Local Recurrence in Rectal Carcinoma: Not One Millimeter but Two Millimeters Is the Limit

By I. Nagtegaal, C. Marijnen, E. Kranenbarg, C. J. van de Velde, J. V. van Krieken. American Journal of Surgical Pathology, 2002

811 citations recorded by the source corpus.

Subfields: Oncology, Surgery

View Paper: https://www.semanticscholar.org/paper/6a4f92a6b819b3309ec48f186fca1f1e4ffe169c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. K. Peeters
2. C. Marijnen
3. E. Kranenbarg
4. Hein Putter
5. T. Wiggers
6. J. Leer
7. C. J. van de Velde
8. L. Påhlman

Citations in the corpus

• A randomized trial of laparoscopic versus open surgery for rectal cancer. (2015, neutral): “(%) I: healthy 156 (22) 65 (19) II: mild systemic disease 386 (55) 211 (61) III: severe systemic disease 131 (19) 61 (18) IV: severe life-threatening systemic disease 5 (1) 1 (<1)”
• The TME Trial After a Median Follow-up of 6 Years: Increased Local Control But No Survival Benefit in Irradiated Patients With Resectable Rectal Carcinoma (2007, background): “Especially for patients with distal lesions, incomplete resection constitutes a major problem: as shown earlier, positive CRM is the most important independent predictor for local failure.(34) Table 4 shows unacceptable high rates of local recurrence in case of positive CRM.”