The TME Trial After a Median Follow-up of 6 Years: Increased Local Control But No Survival Benefit in Irradiated Patients With Resectable Rectal Carcinoma

By K. Peeters, C. Marijnen, I. Nagtegaal, E. Kranenbarg, Hein Putter, T. Wiggers, H. Rutten, L. Påhlman, B. Glimelius, J. Leer and 1 more. Annals of Surgery, 2007

1,192 citations recorded by the source corpus.

Subfields: Oncology, Surgery

View Paper: https://www.semanticscholar.org/paper/ec9773e62806cbc6c603c18f877a45539012b65f

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Citations in the corpus

• Preoperative High-resolution Magnetic Resonance Imaging Can Identify Good Prognosis Stage I, II, and III Rectal Cancer Best Managed by Surgery Alone: A Prospective, Multicenter, European Study (2011, background): “The CR07 and Dutch TME results suggest that LR rates in mobile cancers are substantially reduced if patients with rectal cancer are treated with preoperative short-course radiotherapy.(8,9,32) In both CR07 and the Dutch TME trial, preoperative staging using MRI was not used to determine which patien”
• Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2016 for the treatment of colorectal cancer (2012, background): “fractions in 1 week) ? TME with TME alone to investigate the significance of adding short-course radiotherapy to TME, the 5-year local control rate was significantly higher in the combination therapy group but there was no significant difference between the two groups in the 5-year survival rate [60”
• Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer (2019, methodology): “In the Dutch CKVO 95‐04 trial, which compared preoperative radiotherapy (25 Gy delivered in five fractions in one week) + TME and TME alone to investigate the significance of adding short‐course radiotherapy to TME, the 5‐year and 10‐year local control rates were signifi‐ cantly higher in the combin”
• Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer (2011, background): “fractions in 1 week) ? TME with TME alone to investigate the significance of adding short-course radiotherapy to TME, the 5-year local control rate was significantly higher in the combination therapy group but there was no significant difference between the two groups in the 5-year survival rate [60”