The pedunculopontine nucleus and Parkinson's disease.

By P. A. Pahapill, Andres M. Lozano. Brain : a journal of neurology, 2000

842 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Probing and regulating dysfunctional circuits using deep brain stimulation. (2013, positive): “The PPN, a brainstem structure critical for posture and gait that receives both basal ganglia and spinal cord feedback, is a newer potential target selected in patients with postural instability and frequent falls (Pahapill and Lozano, 2000; Pereira et al., 2008, 2011; Benabid and Torres, 2012).”
Stages in the development of Parkinson’s disease-related pathology (2004, background): “Additional brain regions that become involved in stage 3 include the cholinergic tegmental pedunculopontine nucleus (GarciaRill 1991; Inglis and Winn 1995; Rye 1997; Pahapill and Lozano 2000), the oral raphe nuclei, the cholinergic magnocellular nuclei of the basal forebrain (Candy et al.”
The subthalamic nucleus in the context of movement disorders. (2004, background): “The activation of the PPN increases activity in the nucleus reticularis gigantocellularis, which modulates part of the motor activity over the spinal cord (mostly spinal interneurons) through the reticulopinal tract (Pahapill and Lozano, 2000).”