In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days.

By J. Pillay, Ineke den Braber, N. Vrisekoop, L. Kwast, Rob J. De Boer, J. Borghans, K. Tesselaar, L. Koenderman. Blood, 2010

877 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/533cb2a0fd868a22fbc431baa21165fcb6c783d6

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In Immunology

1. A. Mócsai

Citations in the corpus

• Proteolytically active ADAM10 and ADAM17 carried on membrane microvesicles in human abdominal aortic aneurysms (2015, background): “In contrast, ▶ Figure 5 A-F shows that a significant portion of ADAM10-positive MVs and ADAM17-positive MVs readily stained for CD66, a neutrophil surface marker, even though activated neutrophils typically have a short lifespan (34).”
• Neutrophils: Between Host Defence, Immune Modulation, and Tissue Injury (2015, neutral): “4 days for human neutrophils [29], ten”
• Diverse novel functions of neutrophils in immunity, inflammation, and beyond (2013, background): “In the absence of infection or inflammation, they die by a spontaneous apoptosis program (Geering and Simon, 2011; Witko-Sarsat et al., 2011), likely within 1 d (although some investigators propose this time to be up to 5 d; Pillay et al., 2010).”