Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay.

By Nikki Parker, M. Turk, Elaine Westrick, Jeffrey D. Lewis, P. Low, C. Leamon. Analytical Biochemistry, 2005

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Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology. (2014, methodology): “More importantly, as opposed to methods based on the ex vivo quantification of FR in lysed patient biopsies [297], in vivo imaging modalities might enable the quantification of FR on the surface of cancer cells, actually available for interactions with folate-decorated NPs.”
Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results (2011, neutral): “However, overexpression of FR-α varies strongly between different solid tumors originating from different organ”
Recent progress in tumor pH targeting nanotechnology. (2008, background): “Solid tumors are often characterized by overexpression of specific antigens or receptors on cell surfaces [8-13].”