Angiogenesis in life, disease and medicine

By Peter Carmeliet. Nature, 2005

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Diabetes and Wound Angiogenesis (2017, background): “As the remodeling phase of wound healing ends, the tissue achieves normal vascular permeability, blood flow, and shows normal vascular branching [32].”
Engineering Complex Tissues (2006, neutral): “242,253 Nerve and blood vessel wiring is dependent on common mechanisms, 254 and VEGF signaling may be beneﬁcial to slow or reverse various neural diseases.”
The tumour microenvironment as a target for chemoprevention (2007, background): “Controlling angiogenesis is clearly an important strategy for the treatment of invasive cancer”
Regenerative medicine: Current therapies and future directions (2015, background): “Angiogenesis and nerve growth are known to share certain signaling pathways (95), and this connection has been exploited via the controlled delivery of VEGF using biomaterials to promote axon regrowth in regenerating skeletal muscle (96, 97) (Fig.”
Microvesicles: mediators of extracellular communication during cancer progression (2010, background): “Angiogenesis is vital for tumor survival and tumor growth, and occurs by proliferation of endothelial cells to form a mesh of blood vessels that infiltrate into the tumor, facilitating the supply of nutrients and oxygen for tumor growth as well as removal of waste products (Carmeliet, 2005).”