PEG-grafted chitosan as an injectable thermosensitive hydrogel for sustained protein release.

By N. Bhattarai, Hassna R. Ramay, J. Gunn, Miqin Zhang. Journal of Controlled Release, 2005

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Chitosan-based hydrogels for controlled, localized drug delivery. (2010, methodology): “Use of genipin also showed extended drug release by chitosan hydrogels cross-linked in situ [75,92].”
Chitosan—A versatile semi-synthetic polymer in biomedical applications (2011, background): “Genipin also provides extended drug release by chitosan hydrogels cross-linked in situ [179,190].”
Chitosan-based biomaterials for tissue engineering (2013, background): “Chitosan structure can also be modified to form physical hydrogels: chitosan-g-poly(ethylene glycol) (PEG) graft copolymer is able of self-organization depending on the temperature to form stable hydrogels [73].”
Natural origin biodegradable systems in tissue engineering and regenerative medicine: present status and some moving trends (2007, background): “2005 a , b ) and polyethylene glycol (PEG; Bhattarai et al .”
Polymers for Drug Delivery Systems (2010, methodology): “This approach was used in a study describing the release of model protein bovine serum albumin (BSA) from temperature-responsive chitosan grafted with PEG (PEG-g-chitosan) (55).”