Chitosan-based biomaterials for tissue engineering
By Florence Croisier, C. Jérôme. 2013
1,924 citations recorded by the source corpus.
Abstract Derived from chitin, chitosan is a unique biopolymer that exhibits outstanding properties, beside biocompatibility and biodegradability. Most of these peculiar properties arise from the presence of primary amines along the chitosan backbone. As a consequence, this polysaccharide is a relevant candidate in the field of biomaterials, especially for tissue engineering. The current article highlights the preparation and properties of innovative chitosan-based biomaterials, with respect to their future applications. The use of chitosan in 3D-scaffolds – as gels and sponges – and in 2D-scaffolds – as films and fibers – is discussed, with a special focus on wound healing application.
Subfields: Biomaterials, Surfaces, Coatings and Films
View Paper: https://www.semanticscholar.org/paper/2aa2639f11d84e8d328228aec03607bcfc8bd6ff
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Citations in the corpus
- Chitosan as a Wound Dressing Starting Material: Antimicrobial Properties and Mode of Action (2019, background): “Fibers • non-adherent • high porosity and absorption capacity • mimic the skin’s extracellular matrix • unsuitable for third-degree, eschar, and dry wounds • if the wound is highly exudative, need a secondary dressing [205,206]”
- Scaffolds for 3D Cell Culture and Cellular Agriculture Applications Derived From Non-animal Sources (2019, background): “Chitosan has shown to be a desirable material in tissue engineering due to its biocompatibility (Tamura et al., 2011; Croisier and Jérôme, 2013), antibacterial properties (Benhabiles et al.”