Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.

By Alfredo Castello, Bernd Fischer, Katrin Eichelbaum, R. Horos, B. Beckmann, Claudia Strein, Norman E. Davey, D. Humphreys, T. Preiss, Lars M. Steinmetz and 2 more. Cell, 2012

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A census of human RNA-binding proteins (2014, background): “Independent of my own studies, two proteome-wide pulldown studies of RBPs also isolated FAM98A (Baltz et al., 2012; Castello et al., 2012) and one study verified its binding”
Comprehensive Identification of RNA-Binding Domains in Human Cells (2016, methodology): “Due to their different specificities, each protease also contributes unique 1% FDR RBDpeps to the complete peptide superset (Figure S1G), covering 529 RBPs that highly overlap with human RNA interactomes (Figure 1G) (Baltz et al., 2012; Beckmann et al., 2015; Castello et al., 2012).”
Single-cell RNA-seq: advances and future challenges (2014, positive): “Moreover, variants of the RNA-seq technique globally determine many other RNA-related aspects in the cell, for example, secondary structures of transcripts (32), editing sites (33), transcript stability (34), translation rates (35) and the protein–RNA interactome (36).”
Revealing protein–lncRNA interaction (2015, methodology): “In [103] UV cross-linking and oligo(dT) affinity, purification followed by quantitative MS was used to identify the entire polyadenylated RNA-bound proteome in HeLa cells revealing around 860 pro-”