The developmental origins of the metabolic syndrome.

By Peter D. Gluckman, Mark A. Hanson. Trends in endocrinology and metabolism, 2004

656 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Pediatrics, Perinatology and Child Health, Physiology

View Paper: https://www.semanticscholar.org/paper/516a56d6e608cc2aa5c0ad159dca81f5d245db2e

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In Endocrinology, Diabetes and Metabolism

In Pediatrics, Perinatology and Child Health

In Physiology

Citations in the corpus

Child health, developmental plasticity, and epigenetic programming. (2011, background): “Intrauterine growth restriction (IUGR) is an example of an immediate cryptically maladaptive response to the environment (19, 20, 22).”
Ten Putative Contributors to the Obesity Epidemic (2009, neutral): “Bateson (2001) and Gluckman and Hanson (2004c) independently proposed an anticipatory model based on the considerable comparative evidence that organisms in early development may make adaptive responses which are of no advantage at the time they are made but are able to better match the organism ”
Predictive adaptive responses and human evolution. (2005, background): “Modified, with permission, from [ 6 ]. Opinion”
The nature of nutrition: a unifying framework (2011, background): “Such responses can, however, lead to problems when there is a mismatch between the predicted future environment and that actually encountered (Gluckman and Hanson 2004, 2006b).”
Energetics, Reproductive Ecology, and Human Evolution (2008, background): “followed by high energy availability after birth, a tendency to obesity and the metabolic disease syndrome can result (Gluckman and Hanson 2004).”
Glucocorticoids, prenatal stress and the programming of disease. (2011, neutral): “…adult environment does not match that for which the developmental plasticity is aimed, e.g. if early life undernutrition programmes a ‘thrifty phenotype’ and then food is plentiful, the adult may be at risk of developing metabolic diseases such as diabetes and obesity (Gluckman and Hanson, 2004).”
Web-based method for translating neurodevelopment from laboratory species to humans (2007, background): “There is also increasing concern that conditions during early development may alter the susceptibility to major adult diseases by fetal programming of nutritional or metabolic or behavioral patterns (Gluckman and Hanson, 2004).”
Developmental plasticity and human health (2004, background): “Indeed, people whose birth weights were towards the lower end of the normal range and who subsequently grow up in affluent environments are at increased risk of developing coronary heart disease, type 2 diabetes and hypertensio”