Bone remodeling during fracture repair: The cellular picture.

By A. Schindeler, M. McDonald, Paul B. Bokko, D. Little. Seminars in Cell and Developmental Biology, 2008

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Bone regeneration strategies: engineered scaffolds, bioactive molecules and stem cells Current stage and future perspectives (2018, neutral): “Due to the adapted metabolism in chondrocytes, designed to survive and function in poorly vascularized environments, these cells are located furthest away from the blood vessels [5, 20].”
Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration (2012, background): “The bone healing mechanism and the source of new osteoblasts in fracture sites have been long controversial (Schindeler et al., 2008).”
Inflammation, Fracture and Bone Repair (2016, background): “and replaced by granulation tissue rich in proliferating mesenchymal cells and developing neovasculature embedded in an unorganized extracellular collagen matrix [7,18,23,47].”
Strategies for Controlled Delivery of Growth Factors and Cells for Bone Regeneration (2012, background): “Bone healing and remodeling is accomplished by a complex, coordinated effort of cells, bioactive factors and extracellular matrix to stimulate the proliferation, differentiation and migration of osteoprogenitor cells [15, 16].”