Dual role of hydrogen peroxide in cancer: possible relevance to cancer chemoprevention and therapy.

By M. López-Lázaro. Cancer Letters, 2007

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The emerging role of reactive oxygen and nitrogen species in redox biology and some implications for plasma applications to medicine and biology (2012, background): “As pointed out by many authors including López-Lázaro [136], one consequence of the metabolic differences (also known as the ‘Warburg effect’) is that tumors must generate and maintain relatively high levels of ROS, especially O2 and H2O2.”
Cancer Chemoprevention Through Dietary Antioxidants: Progress and Promise (2008, neutral): “Several studies have also demonstrated that H 2 O 2 can induce cell proliferation, apoptosis resistance, increased angiogenesis, invasion, and metastasis (192).”
A review on the dietary flavonoid kaempferol. (2011, background): “The induction of ROS in cancer cells is emerging as an important anticancer strategy [138, 199-201] and may play an important role in the cytotoxic effects of kaempferol [123, 125, 127].”
Distribution and biological activities of the flavonoid luteolin. (2009, background): “A growing body of research suggests that ROS play a crucial role in cancer development [141-143].”