Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis.

By A. Moretta, C. Bottino, M. Vitale, D. Pende, C. Cantoni, M. Mingari, R. Biassoni, L. Moretta. Annual Review of Immunology, 2001

1,933 citations recorded by the source corpus.

Subfields: Immunology, Organic Chemistry

View Paper: https://www.semanticscholar.org/paper/4f09dc9f9720dd91d76381b2d2d1a71bdc93f463

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In Immunology

1. D. Raulet
2. L. Lanier
3. I. Waldhauer
4. A. Steinle
5. Eric O Long
6. É. Vivier
7. R. Vance
8. L. Moretta

Citations in the corpus

• Unravelling natural killer cell function: triggering and inhibitory human NK receptors (2004, background): “…termed natural cytotoxicity receptors (NCRs), NKp46 (Sivori et al, 1997; Pessino et al, 1998), NKp44 (Vitale et al, 1998; Cantoni et al, 1999) and NKp30 (Pende et al, 1999) possess limited homology with known human molecules and no homology to each other (Moretta et al, 2000, 2001) (Figure 1).”
• Familial and acquired hemophagocytic lymphohistiocytosis (2006, background): “Recent findings indicate that SAP is required for the function of SLAM, thereby participating in intracellular signaling [10], and for cytotoxicity of NK cells and CTLs by association with the receptors 2B4 and NTB-A of the SLAM familiy [76].”
• Activation, coactivation, and costimulation of resting human natural killer cells (2006, background): “Natural cytotoxicity receptors (NCRs) NKp30, NKp44, and NKp46 were identified based on their role in natural cytotoxicity toward tumor cells (62).”
• Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity (2001, background): “It is unknown whether engagement of NKG2D in NK cells results in direct stimulation or supplies a co-stimulatory signal that acts in conjunction with signals from other stimulatory receptor”
• Natural killer cells, viruses and cancer (2001, background): “The structure and function of the NKp30, NKp44 and NKp46 receptors has been reviewed recently by Moretta et al.4,22.”
• Human Dendritic Cells Activate Resting Natural Killer (NK) Cells and Are Recognized via the NKp30 Receptor by Activated NK Cells (2002, background): “Finally, there are two molecules 2B4 and NKp80 that seem to act as activating coreceptors, enhancing the function of the above mentioned NK receptors (16).”
• The Abundant NK Cells in Human Secondary Lymphoid Tissues Require Activation to Express Killer Cell Ig-Like Receptors and Become Cytolytic1 (2004, background): “NCRs mediate tumor and dendritic cell recognition by NK cells (23, 24).”
• Self-reactivity in thymic double-positive cells commits cells to a CD8αα lineage with characteristics of innate immune cells (2004, background): “These include genes encoding cell surface molecules first identified in NK cells (2B4 and NCRp1-”