Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism.

By N. Bhowmick, M. Ghiassi, Andrei V Bakin, M. Aakre, C. Lundquist, M. Engel, Carlos L. Arteaga, H. Moses. Molecular Biology of the Cell, 2001

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Integration of TGF‐β/Smad and Jagged1/Notch signalling in epithelial‐to‐mesenchymal transition (2004, background): “to activate programs leading to formation of stress fibers ( Bhowmick et al, 2001 ).”
Actin dynamics control SRF activity by regulation of its coactivator MAL. (2003, neutral): “For immunoprecipita-mor progression (Bhowmick et al., 2001; Oft et al., 2002; tions, 2 g DNA was transfected per 9 cm plate.”
TGF-β and epithelial-to-mesenchymal transitions (2005, background): “Active EMT signaling events induced by TGF-b target guanine nucleotide exchange factors (GEFs) to activate GTPases of the Rho family, which in turn regulate the cytoskeletal remodeling associated with the gain of cell motility (Bhowmick et al., 2001a; Shen et al., 2001).”
Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis. (2005, background): “Rho-dependent mechanisms are critical to EMT in NMuMG and LLC-PK1 cells.(53,55) EMT in renal interstitial fibrogenesis is mediated by integrin-linked kinase.”