Nanoparticles – known and unknown health risks

By P. Hoet, I. Brüske-Hohlfeld, O. Salata. Journal of Nanobiotechnology, 2004

1,318 citations recorded by the source corpus.

Manmade nanoparticles range from the well-established multi-ton production of carbon black and fumed silica for applications in plastic fillers and car tyres to microgram quantities of fluorescent quantum dots used as markers in biological imaging. As nano-sciences are experiencing massive investment worldwide, there will be a further rise in consumer products relying on nanotechnology. While benefits of nanotechnology are widely publicised, the discussion of the potential effects of their widespread use in the consumer and industrial products are just beginning to emerge. This review provides comprehensive analysis of data available on health effects of nanomaterials.

Subfields: Artificial Intelligence, Software

View Paper: https://www.semanticscholar.org/paper/4d48138f8bcc8acf1c83684db2189e9628218e28

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Citations in the corpus

A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity (2010, background): “…by their ability to gain access to ‘deeper’ skin layers, through hair follicles or sweat ducts, where the barrier function of skin is altered, and weaker (Hoet et al., 2004), and this should be addressed within future studies, as it has not been evidenced for metal particulates at this time.”
Applications and implications of nanotechnologies for the food sector (2008, background): “Translocation of particles through the intestine depends on four main factors: (1) diffusion and accessibility through mucus lining the gut wall, (2) initial contact with enterocytes or M-cells, (3) cellular transport and (4) post-translocation events (Hoet et al. 2004).”
On-chip single nanoparticle detection and sizing by mode splitting in an ultrahigh- Q microresonator (2009, background): “(4-6) can be expressed as �� b�� 2 �� b�� 2 �� ”
Dependence of Nanoparticle Toxicity on Their Physical and Chemical Properties (2018, background): “Nanomaterials can also increase access to the blood stream through ingestion [29, 30].”
Toxicology of nanoparticles: A historical perspective (2007, background): “…recent reviews which have summarized our present understanding of ultrafine/nanoparticle toxicology (Donaldson et al. 2002; Borm & Kreyling, 2004; Hoet et al. 2004; Kreyling et al. 2004; Biswas & Wu 2005; Donaldson et al. 2005; Oberdörster et al. 2005; Donaldson et al. 2006; Lam et al. 2006;…”
Metrics for optimising the multi-dimensional value of resources recovered from waste in a circular economy: A critical review (2017, background): “carbon black and fumed silica for applications in plastic fillers and car tyres, silver nanoparticles coated onto polymers like polyurethane) (Albrecht et al., 2006; Hoet et al., 2004; Jain and Pradeep, 2005).”
Bio-Nanocomposites for Food Packaging Applications (2013, background): “Moreover, nanoparticles may eventually be released into the environment and enter the food chain indirectly [197].”
Grey Goo on the Skin? Nanotechnology, Cosmetic and Sunscreen Safety (2007, background): “Today there is a broad consensus that the principal human health risk may be from inhalation of NP (ECETOC, 2005; Hoet et al., 2004; Maynard, 2006).”
Nanomaterials and nanoparticles: Sources and toxicity (2007, background): “Spherically-shaped solid material with particle diameters smaller than 10 microns can reach the gas exchange surfaces (Figure 26 d) [30], [37].”
Airborne microplastics: Consequences to human health? (2018, neutral): “…translocation via the olfactory nerve (Oberd€orster et al., 2004), by crossing the blood-brain barrier through mechanisms of passive diffusion (especially in small hydrophobic molecules) or carriermediated endocytosis, possibly affecting neuron depolarization (Hoet et al., 2004; Yang et al., 2013).”
Emerging patterns for engineered nanomaterials in the environment: a review of fate and toxicity studies (2014, background): “Exposure pathway determines how an ENM enter an organism, which is generally via the respiratory system, the gastrointestinal system, or the epidermis (Davoren et al. 2007; Hoet et al. 2004; Li et al. 2007; Oberdörster et al. 2005; Warheit et al. 2004).”