Global Spread of Carbapenemase-producing Enterobacteriaceae

By P. Nordmann, T. Naas, L. Poirel. Emerging Infectious Diseases, 2011

2,412 citations recorded by the source corpus.

These resistance traits have been identified among nosocomial and community-acquired infections.

Subfields: Endocrinology, Molecular Medicine

View Paper: https://www.semanticscholar.org/paper/4c1bc39163e3c8693e1b97b6c3658fd6f975c755

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In Endocrinology

1. P. Nordmann
2. L. Poirel
3. J. Pitout
4. F. Codjoe
5. E. Donkor
6. Jung Hun Lee
7. Chang-Ro Lee
8. B. Jeong

In Molecular Medicine

1. L. Poirel
2. P. Nordmann
3. J. Pitout
4. F. Codjoe
5. E. Donkor
6. Jung Hun Lee
7. Chang-Ro Lee
8. B. Jeong

Citations in the corpus

• The difficult-to-control spread of carbapenemase producers among Enterobacteriaceae worldwide. (2014, background): “The carbapenem-hydrolysing class D ß-lactamases Class D ß-lactamases, also named OXAs (for “oxacillinases”) include now more than 400 enzymes, among which only some variants actually possess a carbapenemase activity [93].”
• Global Dissemination of Carbapenemase-Producing Klebsiella pneumoniae: Epidemiology, Genetic Context, Treatment Options, and Detection Methods (2016, background): “Various class B and D carbapenemases have also been detected in hospital-acquired multi-resistant K. pneumoniae (Nordmann et al., 2011a), whereas class C carbapenemases have rarely been reported.”
• The Epidemiology of Carbapenem-Resistant Enterobacteriaceae: The Impact and Evolution of a Global Menace (2017, background): “Since that time, several other VIM types have been recovered from gram-negative bacilli in Greece; globally, the majority of regions have reported outbreaks with VIM-producing Enterobacteriaceae [32, 33, 46, 47].”
• Epidemiology and Diagnostics of Carbapenem Resistance in Gram-negative Bacteria (2019, background): “Class D (also termed oxacillin carbapenemase [OXA enzymes]) enzymes constitute a heterogeneous group of β-lactamases with significant carbapenemase activity, especially OXA-48–type enzymes in Enterobacteriaceae and OXA-23 [24, 25], frequently found in A. baumannii [26, 27].”
• Carbapenem Resistance: A Review (2017, background): “The test may help healthcare facilities to curb and implement rapid containment measures to limit the spread of carbapenemase producers in hospitals [32].”
• Carbapenemase-Producing Klebsiella pneumoniae, a Key Pathogen Set for Global Nosocomial Dominance (2015, background): “Rodríguez-Baño and colleagues in Spain (102) and Karaiskos and Giamarellou (101) in Greece recently published excellent recommendations regarding the treatment of infections with carbapenemase-producing Enterobacteriaceae.”
• The Role of Epidemic Resistance Plasmids and International High-Risk Clones in the Spread of Multidrug-Resistant Enterobacteriaceae (2015, background): “This free movement of plasmid encoded genes responsible for drug resistance has also been central to the recent and rapid global increase in antimicrobial resistance (8).”
• ESCMID guidelines for the management of the infection control measures to reduce transmission of multidrug-resistant Gram-negative bacteria in hospitalized patients. (2014, neutral): “pneumoniae carbapenemase in hospitalized patients [3].”
• Predictors of mortality in bloodstream infections caused by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae: importance of combination therapy. (2012, background): “eastern United States, Israel, and Greece, where they are now considered endemic [1-2,4-6].”