Sacrificial bonds and hidden length dissipate energy as mineralized fibrils separate during bone fracture

By G. Fantner, T. Hassenkam, J. Kindt, J. Weaver, H. Birkedal, L. Pechenik, Jacqueline A. Cutroni, Geraldo A. G. Cidade, Galen Stucky, D. Morse and 1 more. Nature Materials, 2005

911 citations recorded by the source corpus.

Subfields: Biomaterials, Biomedical Engineering, Orthopedics and Sports Medicine

View Paper: https://www.semanticscholar.org/paper/4af5187b817e3ffc07127f4e40b6e7b60e9d865f

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In Biomaterials

In Biomedical Engineering

In Orthopedics and Sports Medicine

Citations in the corpus

Molecular nanomechanics of nascent bone: fibrillar toughening by mineralization (2007, background): “via osteoblast and osteoclast cells [3]), and extrafibrillar matrix properties [10] are important for the macroscopic mechanical properties of bone.”
Merger of structure and material in nacre and bone - Perspectives on de novo biomimetic materials (2009, background): “Other deformation and fracture mechanisms exist in bone at larger hierarchical levels, including the breaking of sacrificial bonds between mineralized fibrils, the formation of microcracks, crack bridging (via collagen fibrils arranged orthogonal to the crack), and the formation of larger plastic zo”
Mineralized structures in nature: Examples and inspirations for the design of new composite materials and biomaterials (2010, neutral): “mechanical properties of the bone composite [45].”
On the Mechanistic Origins of Toughness in Bone (2010, background): “Indeed, single-molecule spectroscopy of fractured bone surfaces has confirmed that the extrafibrillar matrix has properties similar to those of a glue layer between the fibrils—it is relatively weak but ductile and deforms by the successive breaking of a series of sacrificial bonds (68, 71).”
Calcium Phosphate Bioceramics: A Review of Their History, Structure, Properties, Coating Technologies and Biomedical Applications (2017, background): “The implant is then strengthened partly owing to the energy dissipation that occurs through the covalent bonds formed between the collagen molecular chains in the scaffold [495,496].”