Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase‐related protein 2, α‐enolase and heat shock cognate 71

By Alessandra Castegna, M. Aksenov, V. Thongboonkerd, J. Klein, W. Pierce, R. Booze, W. Markesbery, D. Allan Butterfield. Journal of Neurochemistry, 2002

624 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/498af3ee0417a1938fa73bbb947d875d82194cc0

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. V. Calabrese
2. A. Andersson
3. P. Westermark
4. G. Tezel
5. G. Westermark

In Molecular Biology

1. V. Calabrese
2. D. Allan Butterfield
3. A. Andersson
4. I. Dalle-Donne
5. A. Milzani
6. R. Rossi
7. P. Westermark
8. R. Colombo

In Physiology

1. D. Allan Butterfield
2. I. Dalle-Donne
3. A. Milzani
4. R. Rossi
5. R. Colombo
6. D. Giustarini
7. Alessandra Castegna
8. C. Lauderback

Citations in the corpus

• Amyloid β-peptide (1-42)-induced Oxidative Stress and Neurotoxicity: Implications for Neurodegeneration in Alzheimer's Disease Brain. A Review (2002, background): “Creatine kinase (BB isoform) Proteomics; Immunochemistry [53–55] b-Actin Immunochemistry [54] Glutamine synthetase Proteomics (confirmed by immunochemistry) [55] Ubiquitin C-terminal hydrolase L-1 Proteomics [55] Dihydropyrimidnase related protein-2 Proteomics [56] a-Enolase Proteomics [ 56 ] AMYLOI”
• Protein carbonyl groups as biomarkers of oxidative stress. (2003, methodology): “In conclusion, 1D and 2D oxyblots (term that refers to immunoblots of oxidised proteins) appear to provide better information than the spectrophotometric assay, slot immunoblotting, or ELISA about the oxidative status of proteins in a complex mixture like plasma, tissue homogenates, or cellular extr”
• Islet amyloid polypeptide, islet amyloid, and diabetes mellitus. (2011, background): “If the ubiquitin pool is fixed, a change in UCH L-1 activity might deplete ubiquitin available for ubiquitination, or the proteosome may be obstructed by polyubiquitinated proteins (46).”
• Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (2007, background): “Of these proteins, α-enolase has previously been identified as being specifically oxidized in the brains of people with Alzheimer's diseas”
• Oxidative stress in glaucomatous neurodegeneration: mechanisms and consequences. (2006, background): “Glutamine synthetase is a key enzyme that helps maintain the physiological levels of extracellular glutamate through the glutamate-glutamine cycle (Butterfield et al., 1997; Castegna et al., 2002a).”
• Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death. (2002, methodology): “Proteomics has been used for the first time to identify specifically oxidized proteins in AD brain [104,105].”