Myeloid-derived suppressor cells coming of age

By F. Veglia, Michela Perego, D. Gabrilovich. Nature Immunology, 2018

1,565 citations recorded by the source corpus.

Subfields: Epidemiology, Immunology

View Paper: https://www.semanticscholar.org/paper/4708be76b0e47f1a474efd20869ac7ef650eb5fb

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In Epidemiology

1. F. Greten
2. S. Grivennikov

In Immunology

1. S. Grivennikov
2. F. Greten
3. Sandra Hervás-Stubbs
4. I. Melero
5. M. Karin

Citations in the corpus

• Advances in immunotherapy for hepatocellular carcinoma (2021, background): “I.M. receives funding from MINECO SAF2014-52361-R and SAF 2017- 83267-C2-1R; Worldwide Cancer Research Grant (15-1146); the Asociacion Española Contra el Cancer (AECC) Foundation under grant GCB15152947MELE; and the European Union’s Horizon 2020 Program (grant agreement no. 635122 PROCROP).”
• Inflammation and Cancer: Triggers, Mechanisms and Consequences (2019, background): “The same myeloid cells, particularly of granulocytic and monocytic lineage, sometimes referred to as myeloid derived suppressor cell (MDSC)) also contribute to the suppression of anti-tumor responses (Veglia et al., 2018; Yang et al., 2008).”
• Tumor-Associated Macrophages in Tumor Immunity (2020, background): “MDSCs are a type of myeloid leukocytes that is related to immunosuppression (7).”
• Sepsis-induced immunosuppression: mechanisms, diagnosis and current treatment options (2022, background): “MDSCs are a diverse group of immature myeloid cells, including the progenitors of monocytes, neutrophils, and dendritic cells (DCs) that suppress innate and adaptive immune responses [82].”
• Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19 (2020, neutral): “Whatever the mechanism, the immature andmature cells released into the peripheral blood by emergency myelopoiesis may be endowed with immunosuppressive functions, suggesting that myeloid-derived suppressive cells (MDSCs), as detected in cancer, inflammation, and other diseases (Veglia et al., 2018),”
• Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment (2020, neutral): “, 2020) which results in reduced responsiveness to microbial stimuli (Veglia et al., 2018), suggesting that clusters 0 and 6 are composed of dysfunctional monocytes.”