Genome-wide location and function of DNA binding proteins.

By Bing Ren, F. Robert, John J. Wyrick, O. Aparicio, E. Jennings, Itamar Simon, J. Zeitlinger, Jörg Schreiber, N. Hannett, Elenita I. Kanin and 4 more. Science, 2000

1,543 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/46c12f77484f45007c1ba559259c586993ec68d9

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Citations in the corpus

Sparse graphical Gaussian modeling of the isoprenoid gene network in Arabidopsis thaliana (2004, background): “Among these candidate genes, GCY1 and PCL10 are known to be targets of GAL4p [33], and YMR318C has been implicated in another binding-site study [34].”
A computational pipeline for comparative ChIP-seq analyses (2011, background): “It is usually achieved by ChIP followed by microarray analysis (i.e., ChIP-chip) 1,2 , or, more recently, by deep sequencing (ChIP-seq) 3,4 .”
Subcellular localization of the yeast proteome. (2002, background): “Recent genomic techniques combining microarray technologies with either chromatin immunoprecipitation (Ren et al. 2000; Iyer et al. 2001) or targeted DNA methylation (van Steensel et al.”
Genome-wide prediction of transcription factor binding sites using an integrated model (2010, background): “Chromatin immunoprecipitation (ChIP)-chip [2,3] and, more recently, ChIP-seq have become popular and powerful tools to determine TFBSs at a genome-wide scale [3-5].”
Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae. (2007, background): “Exposure to pheromone elevates the expression of a large number of genes significantly, including those encoding proteins required for cell–cell recognition and cell–cell fusion, components of the pathway itself (positive feedback), and factors that downregulate the pathway (negative feedback) [215,”
Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity. (2003, background): “…of histone H3 at lysine 4 (H3-K4) is associated with active chromatin in a wide range of eukaryoticSummary organisms (Strahl et al., 1999; Litt et al., 2001; Boggs et al., 2002; Gendrel et al., 2002; Noma and Grewel, 2002;Set1, the yeast histone H3-lysine 4 (H3-K4) methylase, Reuben and Lin, 2002).”
E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints. (2002, methodology): “At this point, we made several important modifications to protocols previously developed for yeast genome-wide location analysis (Ren et al. 2000) to compensate for the increased complexity of the human genome (see Materials and Methods).”