Early consolidation in human primary motor cortex

By W. Muellbacher, Ulf Ziemann, J. Wissel, N. Dang, M. Kofler, S. Facchini, B. Boroojerdi, W. Poewe, Mark Hallett. Nature, 2002

832 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Cognitive Neuroscience, Neurology

View Paper: https://www.semanticscholar.org/paper/46164103748b34874da5af118ec75242ce72a9df

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Citations in the corpus

Differential Modulation of Motor Cortical Plasticity and Excitability in Early and Late Phases of Human Motor Learning (2007, background): “Karin Rosenkranz,1,2 Aleksandra Kacar,1,3 and John C. Rothwell1 1Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London WC1N 3BG, United Kingdom, 2Centre for”
Neuroplasticity subserving motor skill learning (2011, positive): “Furthermore, downregulating excitability of M1 by lowfrequency TMS (virtual lesion) results in reduced motor memory consolidation (Muellbacher et al., 2002; Robertson et al., 2005), a time-specific effect because it was not observed when TMS was applied 6 hr posttraining (Muellbacher et al., 2002).”
Transcranial magnetic stimulation: a primer. (2007, neutral): “Consolidation of a simple motor skill, phasic pinch force, was disrupted by stimulation selectively over M1, without disruption of other aspects of motor function (Muellbacher et al., 2002).”
Direct current stimulation promotes BDNF-dependent synaptic plasticity: Potential implications for motor learning (2010, neutral): “One interesting cortical target for the application of tDCS has been the primary motor cortex (M1), a region crucially involved in motor execution, memory formation, and consolidation of motor skills in humans and animals (Muellbacher et al., 2002; Rioult-Pedotti et al., 2000; Ungerleider, 1995).”
Current concepts in procedural consolidation (2004, methodology): “For example, applying transcranial magnetic stimulation (TMS) immediately after learning a new skill can establish whether a brain region makes a crucial contribution to an aspect of procedural consolidatio”
Transcranial magnetic stimulation: new insights into representational cortical plasticity (2002, positive): “In accordance with this notion, a recent study by Muellbacher et al. (2002) showed that suprathreshold 1 Hz rTMS over the primary motor cortex caused a lasting interference with motor performance only at an early stage of motor learning but not after consolidation of a newly acquired manual motor…”
Noninvasive cortical stimulation enhances motor skill acquisition over multiple days through an effect on consolidation (2009, methodology): “Noninvasive brain stimulation methods have been used to modulate cortical excitability (10–12) and to perturb initial motor learning and consolidation (8, 13, 14).”
Dissociating the roles of the cerebellum and motor cortex during adaptive learning: the motor cortex retains what the cerebellum learns. (2011, background): “The results from M1 tDCS are in accordance with previous reports suggesting a role of this area in the retention of new motor memories (Muellbacher et al. 2002; Richardson et al. 2006; Hadipour-Niktarash et al. 2007; Galea and Celnik 2009; Hunter et al. 2009; Reis et al. 2009).”
Dynamic reorganization of striatal circuits during the acquisition and consolidation of a skill (2009, neutral): “0 0 5 10 Naive, 13 (5) Early, 16 (8) Late, 15 (6) DMS”
Sleep-dependent learning and memory consolidation. (2004, neutral): “The stabilization phase of consolidation appears to occur largely during wake (Brash- While these categories offer convenient and distinct separations, in real life they rarely operate in isolation. ers-Krug et al., 1996; Muellbacher et al., 2002; Walker et al., 2003a).”
The neurobiology of consolidations, or, how stable is the engram? (2004, background): “In another study, repetitive transcranial magnetic stimulation of M1, but not other brain areas, was reported to disrupt the retention of the behavioral improvement on skilled finger-movement tasks if it was applied within about six hours of training (Muellbacher et al. 2002).”
Preconditioning of Low-Frequency Repetitive Transcranial Magnetic Stimulation with Transcranial Direct Current Stimulation: Evidence for Homeostatic Plasticity in the Human Motor Cortex (2004, background): “…on cortical excitability has been used to induce a temporary cortical dysfunction in healthy subjects (Kosslyn et al., 1999; Hilgetag et al., 2001; Muellbacher et al., 2002; Knecht et al., 2003) or, presumably by normalizing increased levels of excitability, to induce beneficial effects in…”
ReviewMemory Consolidation in Sleep: Dream or Reality (2004, methodology): “In line with the foregoing, Muellbacher et al. (2002) ments) was presented briefly (10 ms) in one quadrant of the visual field followed by a blank screen and thendemonstrated that transcranial magnetic stimulation of the primary motor cortex (M1) disrupted performance a masking pattern (100 ms).”
Sleep-dependent memory consolidation and reconsolidation. (2007, background): “For example, stabilization of some forms of procedural motor memory can develop across 3–6 h of wake [13,16,37].”