Clinical Trials : A Methodologic Perspective

By S. Piantadosi. 2005

699 citations recorded by the source corpus.

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Citations in the corpus

The Randomized Controlled Trial: Basic Considerations (2006, background): “The control can be standard practice, a placebo, or no intervention at all.(3) An RCT has several important features(3,4):”
Restorative Justice Conferencing (RJC) Using Face‐to‐Face Meetings of Offenders and Victims: Effects on Offender Recidivism and Victim Satisfaction. A Systematic Review (2013, result): “Lest it appear that the smaller effect sizes may be due to less time in prison in the RJC group than in the conventional justice group, we can cite a separate study conducted by Strang, Barnes, Sherman, Bennett and Inkpen (2005), which found no significant differences between the RJC and conventiona”
Systematic Review in Software Engineering (2005, background): “Since the late 1980s, systematic research synthesis and meta-analysis reach an especially distinctive methodological status in the health sciences domain [Piantadosi, 1997].”
Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial. (2004, methodology): “The primary test statistic for interim and final analyses was the log-rank test,(39) based on intention to treat including all randomized patients as randomized.(34) Time was defined as number of days from randomization to the first end point (if one occurred), death, date of last contact, or the la”
Building an identifiable latent class model with covariate effects on underlying and measured variables (2004, background): “Biomarkers are used very often as substitutes for observing new cases of cancer in testing treatments for cancer prevention, where event rates are low and a long time may be needed to obtain cancer cases (Piantadosi, 1997).”
Survival Analysis Part I: Basic concepts and first analyses (2003, methodology): “Several introductory texts also describe the basis of survival analysis, for example, Altman (2003) and Piantadosi (1997) .”
An Overview of Research and Evaluation Designs for Dissemination and Implementation (2017, background): “consensus has grown across diverse fields about when certain designs should be used and what sample size requirements and design protocols are necessary to maximize internal validity (42, 87).”
Mobile Health Technology Evaluation (2013, methodology): “The RCT has long been the research gold standard for research for determining the efficacy of health interventions.(14) However, RCTs have a long time lag (i.”
Differential treatment intensity research: a missing link to creating optimally effective communication interventions. (2007, background): “…we are aware of the dangers of adopting terms that are too heavily based on a medical model, our definitions are based directly on the familiar uses of these terms by both professionals and lay persons dealing with medical, and particularly pharmacological, interventions [i.e., Piantadosi, 1997].”
Introduction to SMART designs for the development of adaptive interventions: with application to weight loss research (2014, background): “, free of alternative explanations due to confounding or treatment selection bias [75]) between the experimental treatment and a control conditions in an RCT or between different levels of treatment components in a factorial design, the randomizations in a SMART are aimed at permitting unbiased comp”
Hypothesis Testing (2019, unknown): “We can write the hypothesis test for this example as H0: pmagnesium 1⁄4 pno magnesium vs: HA: pmagnesiumspno magnesium: (4)”
A multicenter randomized trial of breast intensity-modulated radiation therapy to reduce acute radiation dermatitis. (2008, background): “Given that the breast size and the total dose were factors associated with increased skin toxicity,(11,12) the random assignment was stratified for the use of a boost and breast size, and blocked 1:1 to ensure that the two arms were equally balanced.(19) Breast size was defined as small (bra sizes 3”