Capturing and profiling adult hair follicle stem cells

By R. Morris, Yaping Liu, L. Marles, Zaixin Yang, C. Trempus, Shulan Li, Jamie S. Lin, J. Sawicki, G. Cotsarelis. Nature Biotechnology, 2004

1,338 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Urology

View Paper: https://www.semanticscholar.org/paper/4561d2b957a0964b7ee33a172f7662c3012f05a2

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. Elaine Fuchs
2. C. Blanpain
3. Hans Clevers
4. H. Pasolli
5. S. Morrison
6. V. Horsley
7. P. Bonaldo
8. Lisa Polak

In Molecular Biology

1. Elaine Fuchs
2. C. Blanpain
3. Hans Clevers
4. S. Morrison
5. H. Pasolli
6. V. Horsley
7. A. Spradling
8. Y. Hsu

In Urology

1. Elaine Fuchs
2. Hans Clevers
3. C. Blanpain
4. H. Pasolli
5. V. Horsley
6. Y. Hsu
7. S. Morrison
8. A. Spradling

Citations in the corpus

• Characterization and isolation of stem cell-enriched human hair follicle bulge cells. (2005, background): “Upregulation of WNT and TGF β /BMP pathways was a common characteristic of human bulge and mouse bulge cells (summarized in Supplemental Tables 1 and 3) (7, 10), supporting our contention that the defined bulge region is also the stem cell niche in human hair follicles.”
• Cellular and molecular mechanisms of skin wound healing (2024, neutral): “Hair follicle stem cells can regenerate the follicle at every growth phase 52,53 and can regenerate the follicle and interfollicular epidermis after transplantation 54–58 .”
• Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. (2004, background): “ger , morphologically differentiated cells (Figures 3A and Santos et al., 2002; Ivanova et al., 2002; Tumbar et al., 2004; Morris et al., 2004), stained both basal and su- 3D).”
• Dynamics Between Stem Cells, Niche and Progeny in the Hair Follicle (2011, positive): “A decade later, these cells were isolated, characterized and shown to self-renew long-term and contribute to HF lineages and wound-repair (Blanpain et al., 2004; Claudinot et al., 2005; Ito et al., 2005; Morris et al., 2004; Tumbar et al., 2004; Zhang et al., 2009).”
• Regulatory T cells in Skin Facilitate Epithelial Stem Cell Differentiation (2017, positive): “Lineage tracing studies in the SC niche have identified a role for ITGA6-expressing basal cell progenitors and their progeny in adopting a HF fate (Ito et al., 2005; Jaks et al., 2008; Levy et al., 2005; Morris et al., 2004; Tumbar et al., 2004).”
• The international workshop on meibomian gland dysfunction: report of the subcommittee on anatomy, physiology, and pathophysiology of the meibomian gland. (2011, positive): “, hair follicles, sebaceous glands, and epidermis).(84,85) More recent results indicate that epidermal stem cells from regions between hair follicles (interfollicular epidermis) are also bipotent, similar to the hairbulge stem cells,(68) and form two lineages.”
• Epithelial stem cells: turning over new leaves. (2007, positive): “Bulge cells purified by fluorescence-activated cell sorting (FACS) on the basis of their preferred expression of a GFP transgene also differentiated into these lineages upon transplantation (Morris et al., 2004).”
• Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. (2008, background): “Hair-follicle stem cells have also been fate mapped, demonstrating that cells within the bulge give rise to all of the epithelial cells within the hair follicle (Morris et al., 2004) (Figure 3A) and can even transiently contribute to wound repair in the epidermis (Ito et al.”