Mitochondrial transcription factor A regulates mtDNA copy number in mammals.

By Mats I. Ekstrand, M. Falkenberg, A. Rantanen, Chan Bae Park, M. Gaspari, K. Hultenby, P. Rustin, C. Gustafsson, N. Larsson. Human Molecular Genetics, 2004

893 citations recorded by the source corpus.

Subfields: Clinical Biochemistry, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/45365d66255ea3b8f5fd0ef8ee749fed77b5735b

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Clinical Biochemistry

1. C. V. Dang
2. R. Scarpulla

In Molecular Biology

1. C. V. Dang
2. Jung-whan Kim
3. Jason T. Yustein
4. R. Scarpulla
5. G. Semenza
6. Ralph J. Deberardinis
7. Ping Gao
8. M. V. Vander Heiden

In Physiology

1. C. V. Dang
2. Jung-whan Kim
3. R. Scarpulla

Citations in the corpus

• Myc Stimulates Nuclearly Encoded Mitochondrial Genes and Mitochondrial Biogenesis (2005, background): “In transgenic mice, however, overexpression of human TFAM is sufficient to increase mtDNA copy number (12).”
• Transcriptional paradigms in mammalian mitochondrial biogenesis and function. (2008, background): “The stimulatory effect of Tfam is consistent with the observation that overexpression of human Tfam in mice increases mtDNA copy number (59).”