The small RNA chaperone Hfq and multiple small RNAs control quorum sensing in Vibrio harveyi and Vibrio cholerae.

By Derrick H. Lenz, Kenny C. Mok, Brendan N Lilley, R. Kulkarni, Ned S. Wingreen, B. Bassler. Cell, 2004

993 citations recorded by the source corpus.

Subfields: Endocrinology, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/44ff725d8da929d374a1faca4ce642657c578b29

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Citations in the corpus

Regulatory RNAs in Bacteria (2009, background): “…is thought to be ultrasensitive to changes in sRNA and mRNA levels around the critical threshold, especially in the case of multiple, redundant sRNAs, as in the V. cholerae Qrr quorum-sensing system, which is proposed to lead to switch-like ''all or nothing'' behavior (Lenz et al., 2004).”
Systematic deletion of Salmonella small RNA genes identifies CyaR, a conserved CRP‐dependent riboregulator of OmpX synthesis (2008, background): “Similar educated guesses prompted the screen for Hfq-dependent sRNAs to act within quorum-sensing circuits in Vibrio species (Lenz et al., 2004), or to repress Salmonella maltoporin, LamB (Bossi and Figueroa-Bossi, 2007).”
A genome-wide survey of sRNAs in the symbiotic nitrogen-fixing alpha-proteobacterium Sinorhizobium meliloti (2010, background): “transposition [9], bacterial virulence [10], quorum sensing [10,11], plasmid replication [12], function of toxinantitoxin systems [13], and responses to different stress conditions [14].”
Look who's talking: communication and quorum sensing in the bacterial world (2007, background): “2005), triggering a complex response which involves a phosphorelay system and small regulatory RNAs (Lenz et al. 2004).”
Hfq and its constellation of RNA (2011, background): “Hfq-dependent regulators now include sRNA families with several homologue”
Quorum sensing: cell-to-cell communication in bacteria. (2005, background): “The sRNAs, together with Hfq, bind to and destabilize the mRNA encoding the transcriptional activator termed LuxR (not similar to LuxR of V. fischeri) (Lenz et al. 2004).”
Bacterial small RNA regulators: versatile roles and rapidly evolving variations. (2011, background): “Vibrio species have four to five copies of the Qrr genes, at separate chromosomal locations, with varying degrees of divergence (Lenz et al. 2004).”
Microbial Surface Colonization and Biofilm Development in Marine Environments (2015, background): “cholerae, the VarS/VarA TCS; CsrA; and the CsrB, CsrC, and CsrD sRNAs regulate the activity of the QS response regulator LuxO (456), which can also be activated (phosphorylated) by the QS autoinducer-free sensor kinase proteins CqsS and LuxQ via the phosphotransfer protein LuxU (457).”
Stochastic switching in biology: from genotype to phenotype (2017, background): “Many species of bacteria use quorum sensing to coordinate various types of behavior including bioluminescence, biofilm formation, virulence, and antibiotic resistance, based on the local density of the bacterial population [71, 80, 102, 163, 181, 233, 250, 252].”
Biological control of soil-borne pathogens by fluorescent pseudomonads (2005, background): “in the post-transcriptional regulation of bioluminescence and virulenc”
Bacterial quorum sensing: its role in virulence and possibilities for its control. (2012, background): “The two master QS regulators are thus produced in reciprocal gradients with AphA highest at LCD and HapR highest at HCD.”
Quorum sensing in staphylococci. (2008, background): “coli and other species (68), is very weakly expressed in S.”
Bacterial Quorum-Sensing Network Architectures (2009, positive): “Therefore, the simultaneous deletion of the four qrr sRNA genes is required to alter quorum sensing (57).”