RNA Polymerase IV Directs Silencing of Endogenous DNA

By A. Herr, Morten B. Jensen, T. Dalmay, David C. Baulcombe. Science, 2005

778 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/44aff533ae38bdb14c03eabeb7a1ec3ceee7c839

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

In Plant Science

Citations in the corpus

Noncoding transcription by RNA Polymerase Pol IVb/Pol V mediates transcriptional silencing of overlapping and adjacent genes (2008, positive): “The paradox of transcription-dependent gene silencing in plants might be explained by the existence of two structurally and functionally distinct plant-specific RNA polymerases: RNA polymerases IVa/Pol IV and Pol IVb/Pol V (Herr et al., 2005; Kanno et al., 2005; Onodera et al., 2005; Pontier et al.,”
A diverse and evolutionarily fluid set of microRNAs in Arabidopsis thaliana. (2006, background): “…methylation events at the DNA and/or chromatin level, which in turn can lead to heterochromatin formation and maintenance at loci from which the siRNAs arise, such as retroelements and the 5S rDNA arrays (Herr et al. 2005; Kanno et al. 2005; Onodera et al. 2005; Pontier et al. 2005).”
The Arabidopsis Cold-Responsive Transcriptome and Its Regulation by ICE1w⃞ (2005, background): “NRPD1a encodes a plant-specific RNA polymerase IV subunit and is important in small interfering RNA-directed de novo DNA methylation important for silencing of transposon and other repetitive DNA in plants (Herr et al., 2005; Onodera et al., 2005).”
Small RNAs and Their Roles in Plant Development (2009, background): “A putative chromatin remodeling protein, CLASSY1, is also required for siRNA biogenesis and may act together with Pol IV (Smith et al. 2007).”
Directed Polymerase Evolution (2013, background): “This process may be recapitulated and accelerated in the laboratory setting, a process commonly known as directed evolution (directed in the sense that a selection pressure is specified by the experimentalist).”
Partially redundant functions of Arabidopsis DICER-like enzymes and a role for DCL4 in producing trans-acting siRNAs. (2005, neutral): “gene, although to different extents [19].”
Micro RNAs and Short‐interfering RNAs in Plants (2007, background): “Selective disruption of nrpd1a or nrpd1b indicated that efficient silencing at transposons and highly repeated sequences requires the concerted action of both PolIV forms, while a basal level of silencing at low repetitive DNA is only dependent on NRPD1a (Herr et al. 2005; Onodera et al. 2005; Ponti”