Early adverse experience as a developmental risk factor for later psychopathology: Evidence from rodent and primate models

By M. Sanchez, Charlotte O. Ladd, P. Plotsky. Development and Psychopathology, 2001

1,030 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Clinical Psychology

View Paper: https://www.semanticscholar.org/paper/44a15d112e80c29470352011a5a7252918ea4af9

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Citations in the corpus

The developing brain and neural plasticity: Implications for normality, psychopathology, and resilience. (2015, background): “To date, research that has been conducted with rodents and nonhuman primates has demonstrated that traumatic events experienced early in life can modify typical behavioral, neuroendocrine, and immunological responsiveness; brain morphology’ gene expression; and neurochemistry (Meaney, 2001; Meaney e”
The enduring effects of abuse and related adverse experiences in childhood (2006, background): “…coeruleus system also plays a key role in stress (Bremner 1996a) and early stressors lead to long-term decreases in ge-netic inhibition of noradrenergic activity with associated increases in noradrenergic responses to subsequent stressors (Sanchez 2001; Caldji 2000; Francis 1999).”
The link between childhood trauma and depression: insights from HPA axis studies in humans. (2008, positive): “Findings from animal models provide firm evidence for multiple changes in these circuits that occur as a consequence of early-life stress (e.g., Ladd et al., 2000; Sánchez et al., 2001; Meaney and Szyf, 2005 ).”
Maternal stress beginning in infancy may sensitize children to later stress exposure: effects on cortisol and behavior. (2002, background): “Although genetic factors are likely to be important (Young et al 2000), preclinical studies demonstrate that neonatal environmental conditions influence reactivity of the HPA system later in life (Bakshi and Kalin 2000; Sanchez et al 2001).”
Trajectories of brain development: point of vulnerability or window of opportunity? (2003, background): “[49,220]) suggest that glucocorticoids and corticotrophin releasing hormone (CRH) are integrally involved in programming HPA activity for life [140,184].”
Maternal deprivation and the development of stereotypic behaviour (2008, methodology): “Here, we summarise a recent thorough review by Novak et al. (2006); also reviewed by Sackett et al., 1999; Sanchez et al., 2001; Gilmer and McKinney, 2003).”