Filopodia: molecular architecture and cellular functions

By P. Mattila, P. Lappalainen. Nature reviews. Molecular cell biology, 2008

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Tumor angiogenesis and vascular normalization: alternative therapeutic targets (2017, background): “These act as antennae that respond to pro-angiogenic signals, promote motility, help focal adhesions and detect the presence of other cells [14].”
The Actin Cytoskeleton and Actin-Based Motility (2018, background): “By establishing communication with other cells or extracellular molecules, filopodia can guide cell locomotion during normal tissue morphogenesis or cancer metastasis, or form cell–cell junctions in epithelia and neurons (Mattila and Lappalainen 2008).”
Collective cell migration in morphogenesis, regeneration and cancer (2009, background): “Whereas key aspects of single cell migration, such as the molecular control of protrusions, cell–extracellular matrix (ECM) interactions and shape generatio”
The trip of the tip: understanding the growth cone machinery (2009, background): “Filopodia, in particular, are considered to be guidance sensors at the front line of the growth cone and might have a major role in establishing growth cone–substrate adhesive contacts during environmental exploratio”