Collective cell migration in morphogenesis, regeneration and cancer

By Peter Friedl, D. Gilmour. 2009

2,654 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Cell Biology, Molecular Biology, Computational Biology & Bioinformatics

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Citations in the corpus

A benchmark for comparison of cell tracking algorithms (2014, background): “The challenge was organized by members of three research institutions: Center for Biomedical Image Analysis, Masaryk University, Brno, Czech Republic ( CBIA-CZ ); Center for Applied Medical Research, University of Navarra, Pamplona, Spain ( CIMA-ES ); and Erasmus University Medical Center, Rotterdam”
Scalar Active Mixtures: The Nonreciprocal Cahn-Hilliard Model (2020, background): “[48] Peter Friedl and Darren Gilmour, “Collective cell migra-”
Multi-platform analysis of 12 cancer types reveals molecular classification within and across tissues-of-origin (2014, result): “In addition, consistent with previous reports on collective motility in squamous cell carcinomas (Friedl and Gilmour, 2009), RAC and RHO signaling are also elevated in the C2-Squamous-like subtype based on PARADIGM analysis (Table S4A, Figure S7B).”
Chemotaxis in cancer (2011, neutral): “and intravital multiphoton microscopy of live animal”
Interstitial fluid and lymph formation and transport: physiological regulation and roles in inflammation and cancer. (2012, background): “Of course, in vivo tumor cells do not migrate as single cells in a collagen gel, but rather in a complex microenvironment where they are often seen following migratory fibroblasts (140, 243).”
Extracellular Matrix Degradation and Remodeling in Development and Disease (2011, background): “Migration of single cells, including endothelial and immune cells, depends on expression of MMPs at the leading edge and focal degradation of the ECM such that local paths are generated into which cells can freely migrate (van Hinsbergh and Koolwijk 2008; Friedl and Gilmour 2009).”
Cancer invasion and the microenvironment: plasticity and reciprocity. (2011, positive): “Collective migration is prevalent in morphogenesis during development and recapitulated in most epithelial and mesenchymal tumor types (Friedl and Gilmour, 2009; Friedl et al., 1995).”
The impact of jamming on boundaries of collectively moving weak-interacting cells (2012, background): “Collective cell migration is an important characteristic of morphogenesis, wound healing and the growth of a tumor front [1, 2].”
Minimal model of active colloids highlights the role of mechanical interactions in controlling the emergent behavior of active matter (2015, background): “rganize in complex patterns with collective behaviors that serve important biological functions. Examples range from the ﬂocking of birds [1] to the sorting and organization of cells in morphogenesis [2]. Work over the last ten years has shown that many aspects of this complex organization can be ca”