Global burden of alcoholic liver diseases.
By J. Rehm, A. Samokhvalov, K. Shield. Journal of Hepatology, 2013
716 citations recorded by the source corpus.
Liver diseases contribute markedly to the global burden of mortality and disease. This paper provides an overview from a global perspective of the contribution of alcohol to liver diseases. The Global Burden of Disease study methodology was used to estimate the burden of alcohol-attributable liver cirrhosis and alcohol-attributable liver cancer in 2010 as measured by deaths and disability adjusted life years (DALYs). This methodology estimates attributable fractions based on alcohol exposure distribution and relative risks associated with different levels of drinking. Globally, in 2010, alcohol-attributable liver cirrhosis was responsible for 493,300 deaths (156,900 female deaths and 336,400 male deaths) and 14,544,000 DALYs (4,112,000 DALYs for women and 10,432,000 DALYs for men), representing 0.9% (0.7% for women and 1.2% for men) of all global deaths and 0.6% (0.4% for women and 0.8% for men) of all global DALYs, and 47.9% of all liver cirrhosis deaths (46.5% for women and 48.5% for men) and 46.9% of all liver cirrhosis DALYs (44.5% for women and 47.9% for men). Alcohol-attributable liver cancer was responsible for 80,600 deaths (14,800 female deaths and 65,900 male deaths) and 2,142,000 DALYs (335,000 DALYs for women and 1,807,000 DALYs for men). The burden of alcohol-attributable liver cirrhosis and liver cancer is high and entirely preventable. Interventions to reduce alcohol consumption are recommended as a population health priority and may range from taxation increases for alcoholic beverages to increases in screening and treatment rates for alcohol use disorders.
Subfields: Epidemiology, Pathology and Forensic Medicine
View Paper: https://www.semanticscholar.org/paper/4373175877524851629903884cb049a8dceb2a01
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Citations in the corpus
- The Global Burden of Liver Disease: The Major Impact of China (2014, background): “Because the number of ALD is increased at an alarming rate over the last 20 years, the Chinese Society of Hepatology established the fatty liver and ALD study group in 2001 and has published a series of clinical practice guidelines for diagnosis and management of ALD since 2003.17 However, in China,”
- Contemporary Epidemiology of Chronic Liver Disease and Cirrhosis (2019, neutral): “Yellow (40-50), Yellow-Orange (50-60), Orange-Red (60-70), Red (>70) Moon et al. Page 21 Clin Gastroenterol Hepatol.”
- Mortality due to cirrhosis and liver cancer in the United States, 1999-2016: observational study (2018, background): “27 The current study extends such data by that, in recent years, the rate of change in mortality is greatest for young people.”
- Diagnosis and Treatment of Alcohol‐Associated Liver Diseases: 2019 Practice Guidance From the American Association for the Study of Liver Diseases (2020, neutral): “%CDT 21% (6-45) 100% (96-100) 100% (39-100) —”
- Molecular mechanisms and physiological functions of mitophagy (2021, neutral): “Alcoholic liver disease (ALD) is caused by excess alcohol intake (Rehm et al , 2013).”
- The relationship between different dimensions of alcohol use and the burden of disease—an update (2017, background): “Liver disease is linked clearly to alcohol [277], evidenced by several ICD codes for alcoholic liver diseases (Table 1), including simple alcoholic steatosis, hepatitis, fibrosis and cirrhosis and superimposed hepatocellular carcinoma, which is part of alcohol-attributable cancers (see above).”