Chitosan disrupts the barrier properties of the outer membrane of gram-negative bacteria.

By I. Helander, E. Nurmiaho‐Lassila, R. Ahvenainen, J. Rhoades, S. Roller. Journal of food microbiology, 2001

1,278 citations recorded by the source corpus.

Subfields: Microbiology, Organic Chemistry, Pharmaceutical Science

View Paper: https://www.semanticscholar.org/paper/41ffe5faf60bd06a555f8ad2d3f814e2902e3c2b

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In Microbiology

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Citations in the corpus

• Chitin and Chitosan Preparation from Marine Sources. Structure, Properties and Applications (2015, background): “5) and degree of acetylation of chitosan [183–185].”
• Evaluation of different factors affecting antimicrobial properties of chitosan. (2016, background): “b the interaction of diffused hydrolysis products with microbial DNA, which leads to the inhibition of the mRNA and protein synthesis [104,10,19,21,77]; c chitosan also inhibits the microbial growth by the chelation of nutrients and essential metals[104,11,50,51,16]; d chitosan on the surface of the”
• Chitosan kills bacteria through cell membrane damage. (2004, methodology): “3 allows interactions with negatively charged microbial cell membranes that lead to the leakage of intracellular constituents (Papineau et al., 1991; Sudarshan et al., 1992; Helander et al., 2001).”
• Chitosan-Based Coating with Antimicrobial Agents: Preparation, Property, Mechanism, and Application Effectiveness on Fruits and Vegetables (2016, methodology): “Themicrostructure of chitosan coating was observed by AFM and SEM in the investigation of Xing et al. [1, 2, 18].”
• A Biopolymer Chitosan and Its Derivatives as Promising Antimicrobial Agents against Plant Pathogens and Their Applications in Crop Protection (2011, background): “Moreover, it has been reported that asparagine N-conjugated chitosan oligosaccharide that possesses two positively charged sites provides strong interaction with carboxyl-negative charges on the bacteria cell wall [354, 372].”
• Preparation and Characterization of Chitosan/Zinc Oxide Nanoparticles for Imparting Antimicrobial and UV Protection to Cotton Fabric (2012, background): “At any event, however, the antibacterial activity could be attributed to the antibacterial effect of chitosan [19] and photocatalysis of ZnO.”