Cannabinoid CB2 receptors: immunohistochemical localization in rat brain.

By J. Gong, E. Onaivi, H. Ishiguro, Qing-rong Liu, P. Tagliaferro, A. Brusco, G. Uhl. Brain Research, 2006

820 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Endocrine and Autonomic Systems, Pharmacology

View Paper: https://www.semanticscholar.org/paper/41b1ea535b1c09b945bd4dd192571b14d3000b31

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. R. Pertwee
2. V. Di Marzo
3. U. Kumar
4. Shenglong Zou
5. R. Ross
6. George Kunos
7. K. Mackie
8. R. Mechoulam

In Endocrine and Autonomic Systems

1. R. Pertwee
2. V. Di Marzo

In Pharmacology

1. R. Pertwee
2. V. Di Marzo
3. U. Kumar
4. Shenglong Zou
5. George Kunos
6. R. Ross
7. P. Pacher
8. S. Batkai

Citations in the corpus

• The Endocannabinoid System as an Emerging Target of Pharmacotherapy (2006, background): “…in cells of the immune and hematopoietic systems (Munro et al., 1993) but recently were found to be present in the brain (Van Sickle et al., 2005; Gong et al., 2006), in nonparenchymal cells of the cirrhotic liver (Julien et al., 2005), in the endocrine pancreas (Juan-Pico et al., 2005), and in…”
• Effects of cannabinoids and cannabinoid‐enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes (2011, background): “…(Mechoulam, 2000), and most of its effects are attributed to the activation of the cannabinoid CB1 and CB2 receptors, two G-protein-coupled receptors (GPCR) widely expressed in mammalian tissues (Matsuda et al., 1990; Munro et al., 1993; Van Sickle et al., 2005; Gong et al., 2006; Pertwee, 2008).”
• CB2: a cannabinoid receptor with an identity crisis (2010, methodology): “However, RT-PCR demonstrated the presence of CB2 mRNA, at levels too low to be quantified.”
• International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2 (2010, background): “…including immune cells (Howlett et al., 2002), and 2) that CB 2 receptors are expressed by some neurons, both within the brain and elsewhere (Skaper et al., 1996; Ross et al., 2001a; Van Sickle et al., 2005; Wotherspoon et al., 2005; Beltramo et al., 2006; Gong et al., 2006; Baek et al., 2008).”
• Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System (2018, background): “However, this concept has been challenged recently by several studies demonstrating the expression of the CB2R in the brain, albeit to a much lower extent in comparison to the immune system or the CB1R [57].”
• The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9‐tetrahydrocannabinol, cannabidiol and Δ9‐tetrahydrocannabivarin (2008, background): “CB1 receptors are also expressed by some non-neuronal cells, including immune cells, and CB2 receptors by some neurons both within and outside the brain (Skaper et al., 1996; Ross et al., 2001; Van Sickle et al., 2005; Wotherspoon et al., 2005; Beltramo et al., 2006; Gong et al., 2006).”