CB2: a cannabinoid receptor with an identity crisis

By Brady K. Atwood, K. Mackie. British Journal of Pharmacology, 2010

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Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System (2018, background): “Although the expression of the CB2R in the CNS and PNS is comparatively limited, it is undeniable that the CB2R plays an active role in neurological activities, such as nociception, drug addiction and ne roinflammation [55,56].”
An introduction to the endogenous cannabinoid system (2015, background): “, nerve injury) (27, 28), and see (29) for a discussion of the caveats on examining CB2 in the brain.”
Neurobiological Interactions Between Stress and the Endocannabinoid System (2016, background): “There is also evidence that they are possibly expressed by some neurons (Atwood et al, 2012; Van Sickle et al, 2005), but the role of these putative neuronal CB2 receptors has yet to be established (Atwood and Mackie, 2010).”