Lateral presynaptic inhibition mediates gain control in an olfactory circuit

By Shawn R. Olsen, Rachel I. Wilson. 2008

547 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Ecology, Evolution, Behavior and Systematics, Sensory Systems

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Citations in the corpus

Divisive normalization in olfactory population codes (2010, methodology): “A PN's odor responses are disinhibited by silencing input to other glomeruli (Olsen and Wilson, 2008; Asahina et al., 2009), implying that lateral interactions are mainly inhibitory.”
Parvalbumin-expressing interneurons linearly control olfactory bulb output (2013, unknown): “In the Drosophila antennal lobe, an insect analog of the olfactory bulb, the strength of inhibition is proportional to the total amount of excitatory sensory input (divisive normalization) (Olsen et al., 2010; Olsen and Wilson, 2008).”
Neuronal mechanisms underlying innate and learned olfactory processing in Drosophila. (2019, background): “67 68 Lateral inhibition also acts at the first synapse in the olfactory system, between ORNs and 69 projection neurons (PNs), where local interneurons inhibit release from ORN presynaptic 70 terminals [11-13].”
A Complete Electron Microscopy Volume of the Brain of Adult Drosophila melanogaster (2017, background): “Mixed I/O arrangements can be physiologically and behaviorally important; for example, in the antennal lobe, inhibitory inputs into olfactory receptor neuron axons are known to mediate gain control and temporal sharpening (Olsen and Wilson, 2008; Raccuglia et al., 2016; Root et al., 2008).”
Odor Discrimination in Drosophila: From Neural Population Codes to Behavior (2013, background): “…as a mechanism for enhancing contrast (Barlow, 1953; Hartline et al., 1956; Kuffler, 1953), exerting gain control (Barlow, 1961; Olsen et al., 2010; Olsen and Wilson, 2008; Root et al., 2008), or binding neurons representing different stimulus features in synchrony (Gray et al., 1989; Laurent and…”
Olfactory information processing in Drosophila. (2009, unknown): “The second major gain control mechanism is inhibition mediated by local neurons which can be either interglomerular [33] or intraglomerular [34].”
Nonrandom Local Circuits in the Dentate Gyrus (2008, background): “This adaptive gain control function has recently been demonstrated directly for glomerular-layer interneurons in the insect analog of the olfactory bulb (Olsen and Wilson, 2008).”
Quantitative neuroanatomy for connectomics in Drosophila (2015, background): “In reality, dendro-dendritic and axo-axonic synapses are present in both invertebrates (Wilson and Mainen, 2006; Olsen and Wilson, 2008) and vertebrates (Rudomin and Schmidt, 1999; Wilson and Mainen, 2006; Pinault et al., 1997).”
Cellular-resolution population imaging reveals robust sparse coding in the Drosophila Mushroom Body (2011, background): “Although there are clearly gain control mechanisms in the antennal lobe that act to normalize different levels of ORN input (Olsen and Wilson, 2008; Root et al., 2008), our results indicate that this process is not complete since net input to the system influences the extent of activity in the MB.”