Spread of HTLV-I Between Lymphocytes by Virus-Induced Polarization of the Cytoskeleton

By T. Igakura, J. Stinchcombe, P. Goon, G. Taylor, J. Weber, G. Griffiths, Yuetsu Tanaka, M. Osame, C. Bangham. Science, 2003

760 citations recorded by the source corpus.

Subfields: Agronomy and Crop Science, Ecology, Evolution, Behavior and Systematics, Immunology

View Paper: https://www.semanticscholar.org/paper/4046aad93887075010bce8f9f7de2beba242a82d

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In Immunology

1. Dimiter S. Dimitrov
2. Q. Sattentau

Citations in the corpus

• HIV: cell binding and entry. (2012, background): “HIV, along with viruses (Igakura et al. 2003; Yang et al. 2004), can take advantage of this pathway to augment infection efficiency and dissemination (Fig.”
• Avoiding the void: cell-to-cell spread of human viruses (2008, background): “The observation that the microtubule organizing centre (MTOC) polarizes at HTLV-1 (Ref”
• Virus Entry: Open Sesame (2006, neutral): “Initially described for the transfer of the human T cell leukemia virus type 1 (HTLV-1) from infected to uninfected T cells, these areas of intimate contact between the infected and uninfected cells were recognized to have features in common with immunological synapses (Igakura et al., 2003).”
• iArc monogrAphs on the evAluAtion oF cArcinogenic risks to humAns (2012, background): “A characteristic of HTLV-1 is that it is mainly spread through cell-to-cell contact, although the exact mechanism is still a matter of debate (Igakura et al., 2003).”
• The protein network of HIV budding. (2003, methodology): “(e.g., see Igakura et al., 2003; McDonald et al., 2003) GST fusion proteins were purified by glutathione affinity chromatography, cleaved to remove glutathione, and repurified by conven-and because the primary sites of virus release likely tional chromatography (Pornillos et al., 2002a).”
• HIV-1 Cell to Cell Transfer across an Env-induced, Actin-dependent Synapse (2004, background): “The other work ( 2 ) describes a model in which HTLV-1 moves from infected to uninfected T cells.”
• Virus entry: molecular mechanisms and biomedical applications (2004, background): “Some viruses enter cells through direct cell-to-cell contacts, using structures that are formed by the polarized cytoskeleton, adhesion molecules and viral proteins at the infected cell junction, which is known as the 'virological synapse' 9 .”