The impact of next-generation sequencing technology on genetics.

By Elaine R. Mardis. Trends in Genetics, 2008

2,229 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/400824c2470932abefb8a4dadbbdd3bf5c01d711

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In Molecular Biology

Citations in the corpus

Population Genomics of Parallel Adaptation in Threespine Stickleback using Sequenced RAD Tags (2010, background): “(NGS) [11–13], the emerging field of population genomics now”
Genomic Selection in Plant Breeding (2011, background): “Details on the mechanisms of current NGS platforms, the available bioinformatics tools for sequence data analysis and SNP identification, and their impact on future genetics studies and crop improvement can be found in several recent review articles (Deschamps and Campbell, 2010; Mardis, 2008; Shend”
Metagenomics - a guide from sampling to data analysis (2012, background): “Excellent reviews of these technologies are available [20,21], but a brief sum-mary is given here with particular attention to metagenomic applications.”
Genome assembly reborn: recent computational challenges (2009, background): “New challenges are posed by recent advances in genome sequencing technologies [12, 13], both due to the sheer size of the data that need to be processed (a single sequencing instrument can provide throughput similar to what was previously only achievable at a genome center), and due to the character”
TCC: an R package for comparing tag count data with robust normalization strategies (2013, background): “…(HTS), also known as next-generation sequencing (NGS), is widely used to identify biological features such as RNA transcript expression and histone modification to be quantified as tag count data by RNA sequencing (RNA-seq) and chromatin immunoprecipitation sequencing (ChIP-seq) analyses [1,2].”
Next‐generation sequencing technologies for environmental DNA research (2012, methodology): “In the SOLiD system, two slides can be processed in a single run; one slide receives sequencing reagents while the second slide is being imaged (Mardis 2008b).”
A SPECTRAL APPROACH INTEGRATING FUNCTIONAL GENOMIC ANNOTATIONS FOR CODING AND NONCODING VARIANTS (2016, background): “The tremendous progress in massively parallel sequencing technologies enables investigators to efficiently obtain genetic information down to single base resolution on a genome-wide scale [1, 2, 3].”
Applications of next-generation sequencing to phylogeography and phylogenetics. (2013, background): “Despite this obvious potential, NGS has been slow to take root in phylogeography and phylogenetics compared to other fields like metagenomics and disease genetics (Mardis, 2008).”