In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens.

By Steffen Jung, D. Unutmaz, P. Wong, G. Sano, K. de los Santos, T. Sparwasser, Shengjia Wu, Srilatha Vuthoori, Kyung Ko, F. Zavala and 3 more. Immunity, 2002

1,936 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/3e99542f02e719d4d64bb0097f47e1e6e2f9a0bf

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. Steffen Jung
2. Eric G. Pamer
3. Guido Kroemer
4. L. Zitvogel
5. F. Geissmann
6. A. Luster
7. H. Hammad
8. R. Steinman

Citations in the corpus

• Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement (2006, background): “However, it may be important that our work involved imaging based on EGFP expression by what may be a much larger and potentially distinct fraction of DCs, based on control of the reporter by the CD11c (21) or MHC class II (20) gene regulatory regions.”
• Cross‐presentation, dendritic cell subsets, and the generation of immunity to cellular antigens (2004, background): “Several studies have shown that antigen presentation by bone marrow-derived cells (31, 79, 80) or CD11cþ cells (70, 71) is important for responses to pathogens and other antigens, implicating DCs in this process.”
• Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche (2011, methodology): “…cannot be explained by nonspecific cell death because in vivo depletion of neutrophils and Gr-1hi MO using anti–Gr-1 (Ly6G/ C) antibody or depletion of dendritic cells using DT administration in CD11c-DTR mice (Jung et al., 2002) did not lead to any progenitor mobiliza- tion (unpublished data).”
• Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8α+ dendritic cells (2011, methodology): “CD11c-DTR mice (Jung et al., 2002) were provided by D. Littman (New York University School of Medicine, New York, NY).”