The WHO Classification of Tumors of the Nervous System

By P. Kleihues, D. Louis, B. Scheithauer, L. Rorke, Guido Reifenberger, P. Burger, W. Cavenee. Journal of Neuropathology and Experimental Neurology, 2002

1,935 citations recorded by the source corpus.

Subfields: Genetics, Neurology

View Paper: https://www.semanticscholar.org/paper/3dfed9d1fa143bd82f987dbaf55b52b090015b4b

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. H. Ohgaki
2. P. Kleihues
3. Guido Reifenberger
4. Richard J. Gilbertson
5. R. Jenkins
6. McKinsey L. Goodenberger

Citations in the corpus

• Radial glia cells are candidate stem cells of ependymoma. (2005, background): “Ependymomas occur most commonly in the wall of the cerebral ventricles or in the spinal canal and they display characteristic ultrastructural and immunohistochemical features of normal ependymal cells (Kleihues et al., 2002; Liberski, 1996).”
• Tumorigenesis in the brain: location, location, location. (2007, background): “Tumors of the central nervous system (CNS) account for less than 2% of all malignancies, yet brain tumors are the leading cause of cancer-related death in children and the fourth leading cause in adults (1).”
• Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. (2006, methodology): “Tumor specimens and primary tumor cultures Following informed consent , tumor samples classified as GBM based on World Health Organization ( WHO ) criteria were obtained from patients under - going surgical treatment at the National Institutes of Health in accordance with the appropriate Institution”
• SSEA-1 Is an Enrichment Marker for Tumor-Initiating Cells in Human Glioblastoma (2009, methodology): “Following informed consent, tumor samples classified as glioblastoma, based on the World Health Organization (WHO) criteria, were obtained from patients undergoing surgical treatment at the National Institutes of Health (NIH) in accordance with the appropriate Institutional Review Boards (Kleihues e”
• Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas. (2005, methodology): “Histologic diagnoses were reevaluated according to the new WHO classification of tumors of the nervous system (9, 10).”
• O-(2-[18F]fluoroethyl)-L-tyrosine PET combined with MRI improves the diagnostic assessment of cerebral gliomas. (2005, methodology): “Some studies used image-guided tumour biopsy or post-mortem specimens for correlation and reported on discrepancies between the real tumour extent and signal abnormalities in MRI (Watanabe et al., 1992; Jansen et al., 2000).”