Cholesterol metabolism in the brain

By J. Dietschy, S. Turley. Current Opinion in Lipidology, 2001

945 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology, Surgery

View Paper: https://www.semanticscholar.org/paper/3de3e6ab32917a5aaa7fe2b7f2b8725014021000

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Rudolph E. Tanzi
2. George Bartzokis
3. Tae‐Wan Kim
4. G. Di Paolo

In Oncology

1. George Bartzokis

In Surgery

1. George Bartzokis
2. Juan Zhang
3. Qiang Liu

Citations in the corpus

• Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer's disease. (2004, background): “All brain cholesterol is synthesized de novo by oligodendrocytes and the human brain, which is approximately 2% of the body by weight, contains approximately 25% of the body’s membrane cholesterol [65,163].”
• Alzheimer's disease: the cholesterol connection (2003, background): “Cholesterol metabolism in the brain Overall, the brain is the organ with the highest content of cholesterol in the body, containing ∼20% of total body cholesterol, but accounting for only ∼2% of body mass (for review, see ref”
• Linking Lipids to Alzheimer’s Disease: Cholesterol and Beyond (2011, background): “In the brain, cholesterol is present mainly in its unesterified form in myelin sheaths and the cellular membranes of glial cells and neuron”