Regulation of dendritic spine morphology and synaptic function by Shank and Homer.

By C. Sala, V. Piëch, Nathan R. Wilson, M. Passafaro, Guosong Liu, Morgan Sheng. Neuron, 2001

742 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/3dbb59a08977bc96543ef5c8b78dfccd4ec4c1c1

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. C. Hoogenraad
2. M. Sheng
3. H. Hering
4. Alban Latremoliere
5. Mark F. Bear
6. H. Zoghbi
7. Clifford J. Woolf
8. R. Ji

In Cognitive Neuroscience

1. Mark F. Bear
2. H. Zoghbi
3. M. Sheng
4. Clifford J. Woolf
5. C. Hoogenraad
6. Thomas Bourgeron

Citations in the corpus

• Synaptic dysfunction in neurodevelopmental disorders associated with autism and intellectual disabilities. (2012, background): “Consistent with the important role of Shank proteins in synaptic function, overexpression of Shank1 in hippocampal neurons leads to increased maturation and size of dendritic spines (Sala et al. 2001).”
• Control of Dendritic Arborization by the Phosphoinositide-3′-Kinase–Akt–Mammalian Target of Rapamycin Pathway (2005, methodology): “Spine analysis was performed as described previously (Sala et al., 2001).”
• Lipid Rafts in the Maintenance of Synapses, Dendritic Spines, and Surface AMPA Receptor Stability (2003, methodology): “3C), another major scaffold protein of the PSD (Naisbitt et al., 1999; Sala et al., 2001).”
• Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity (2009, positive): “The interaction between Homer1b and IP3R and between Shank1 and Homer1b/c controls local Ca(21) release from the endoplasmic reticulum upon mGluRs activation.(266,267) Figure 13.”
• The role of the Rho GTPases in neuronal development. (2005, background): “Given that Shank plays a role in spine morphogenesis (Sala et al. 2001), Shank may recruit -Pix and PAK to spines for the regulation of post-synaptic structure (Park et al. 2003).”
• Dentritic spines : structure, dynamics and regulation (2001, background): “, promoted the maturation of mushroom spines in developing neurons, and increased the size of spine heads in mature neurons without an effect on spine numbe”