Adipose tissue, adipokines, and inflammation.

By G. Fantuzzi. Journal of Allergy and Clinical Immunology, 2005

2,729 citations recorded by the source corpus.

Subfields: Endocrine and Autonomic Systems, Epidemiology, Physiology

View Paper: https://www.semanticscholar.org/paper/3d1f817fafc2b0f0840d98cb9ad9b995211d31b7

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Citations in the corpus

Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and co-morbid conditions. (2010, background): “Cytokines and adipocytokines including TNF-a, interleukin-6, leptin, and adiponectin (Fantuzzi, 2005; Wellen and Hotamisligil, 2005) are increasingly recognized as important regulators of both insulin sensitivity and inflammation, and a dysregulation of their levels and/or functions has been shown i”
Deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice (2009, neutral): “These inflammatory cells furnish cytokines, growth factors, chemokines, and proteases in WAT11,12.”
Obesity and inflammation: the linking mechanism and the complications (2016, background): “Furthermore, cross-talk between lymphocytes and adipocytes can lead to immune regulation [16].”
Adipokines as emerging mediators of immune response and inflammation (2007, background): “It is important to underline that the term 'adipokine' is generally applied to biologically active substances found in the adipocytes of WAT; however, these factors might be synthesized at other sites and participate in functions unrelated to those within WAT”
Adipocytokines: mediators linking adipose tissue, inflammation and immunity (2006, background): “However, although macrophages in adipose tissue seem to be the main source of TNF, adipocytes contribute almost one third of the IL-6 concentration in the circulation of patients who are obes”
Molecular Inflammation: Underpinnings of Aging and Age-related Diseases (2008, background): “WAT comprises the vast majority of adipose tissue in the organism and is the site of energy storage; whereas, the main role of BAT is for non-shivering thermogenesis, particularly in small mammals and human neonates (Fantuzzi, 2005).”
Insulin resistance: Review of the underlying molecular mechanisms (2018, background): “adiponectin, and apelin, which are generated and released by adipocytes and are involved in obesity and IR (Fantuzzi, 2005).”
Fat Treg cells: a liaison between the immune and metabolic systems (2009, background): “Visceral fat produces a number of inflammatory cytokines and chemokines (such as leptin, tumor necrosis factor-α (TNF-α), macrophage chemoattractant protein-1 and interleukin-6 (IL-6), among others), whose production can be pathologically dysregulated in the obese state, contributing in an important”
Adiponectin, a Therapeutic Target for Obesity, Diabetes, and Endothelial Dysfunction (2017, background): “Brown adipocytes are particularly present in small mammals and human neonates, and contain several smaller lipid droplets (multilocular appearance) [9].”