Tumor resistance to apoptosis

By Simone Fulda. International Journal of Cancer, 2009

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Apoptosis and Molecular Targeting Therapy in Cancer (2014, background): “Conflict of Interests The authors declare that there is no conflict of interests regarding the publication of this paper.”
Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis (2015, background): “Disrupted balance of pro- and anti-apoptotic proteins by underexpression and/or overexpression and dysregulated expression of microRNA, which regulates oncogenes or tumor suppressor genes, were observed in cancer cells [6–8], resulting in overproliferation and/or dysfunctional removal of cancer cell”
Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies (2016, background): “Deregulation of this death process is associated with unchecked cell proliferation, development and progression of cancer and cancer resistance to drug therapies [3,4].”
Anti-apoptosis and cell survival: a review. (2011, background): “This is achieved by balancing pro- and anti-apoptotic machineries [38,42,43].”
Targeting mitochondria for cancer therapy (2010, background): “jpg"/> Evasion of cell death is a hallmark of human cancers and a major cause of treatment failur”
Targeting IAP proteins for therapeutic intervention in cancer (2012, background): “and represents a key cause of resistance to current treatment approache”