Role of axonal transport in neurodegenerative diseases.

By K. D. De Vos, A. Grierson, S. Ackerley, Christopher C. J. Miller. Annual Review of Neuroscience, 2008

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Trafficking and proteolytic processing of APP. (2012, neutral): “Cite this article as Cold Spring Harb Perspect Med 2012;2:a006270 11 w w w .p e rs p e c ti v e si n m e d ic in e .o rg pathogenesis (De Vos et al. 2008; Morfini et al. 2009).”
Stochastic models of intracellular transport (2013, background): “On the other hand, various types of dysfunction in protein trafficking appear to be a major contributory factor to a number of neurodegenerative diseases associated with memory loss including Alzheimers (de Vos et al., 2008).”
Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex (2010, background): “Based on this principle, disruption of axonal transport has long been proposed as a potential mechanism in human neurodegenerative diseases (Duncan and Goldstein, 2006; De Vos et al., 2008).”
Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease. (2010, neutral): “In particular, primary or secondary axonal transport defects can result in neuronal degeneration in several neurological diseases (Chevalier-Larsen and Holzbaur, 2006; De Vos et al., 2008; Roy et al., 2005).”