Anxiety Reduction through Detachment: Subjective, Physiological, and Neural Effects

By Raffael Kalisch, Katja Wiech, Hugo D. Critchley, Ben Seymour, John P. O'Doherty, D. Oakley, P. Allen, R. J. Dolan. Journal of Cognitive Neuroscience, 2005

334 citations recorded by the source corpus.

The ability to volitionally regulate emotions helps to adapt behavior to changing environmental demands and can alleviate subjective distress. We show that a cognitive strategy of detachment attenuates subjective and physiological measures of anticipatory anxiety for pain and reduces reactivity to receipt of pain itself. Using functional magnetic resonance imaging, we locate the potentialsite andsourceof this modulation of anticipatory anxiety in the medial prefrontal/anterior cingulate and anterolateral prefrontal cortex, respectively.

Subfields: Cognitive Neuroscience, Experimental and Cognitive Psychology

View Paper: https://www.semanticscholar.org/paper/39d6e00d7623c4bd3a030479363dd6fc873e139d

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Citations in the corpus

Putting Feelings Into Words (2007, positive): “…activations have been widely distributed across prefrontal cortex; however, a number of these studies have found RVLPFC activity during reappraisal (Beauregard, Levesque, & Bourgouin, 2001; Kalisch et al., 2005; Levesque et al., 2003; Phan et al., 2005; Ochsner et al., 2004; Schaefer et al., 2003).”
Common and differential neural networks of emotion regulation by Detachment, Reinterpretation, Distraction, and Expressive Suppression: A comparative fMRI investigation (2014, background): “Detachment has been repeatedly associatedwith activation in dorsal anterior cingulate (dACC), dorsal and anterior portions of the medial prefrontal cortex (mPFC), more right-sided DLPFC, middle and superior frontal cortex aswell as IPC, andwith a reduction of amygdala activation (Erk et al., 2010a; ”
Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. (2007, background): “These regions are activated by emotional conflict (102), track levels of emotional arousal (111), correlate with autonomic activity (112, 113), and respond in anticipation of an aversive event (96), among related functions.”
Prefrontal-subcortical pathways mediating successful emotion regulation. (2008, positive): “By contrast, prior reappraisal instructions have either given equal emphasis to positive-generation and negative-blunting appraisals ( Johnstone et al., 2007; Ochsner et al., 2002, 2004; Phan et al., 2005; Urry et al., 2006) or have emphasized distancing and detachment (Eippert et al., 2007; Kalisc”
Heart Rate Variability, Prefrontal Neural Function, and Cognitive Performance: The Neurovisceral Integration Perspective on Self-regulation, Adaptation, and Health (2009, background): “Importantly, these inhibitory functions have been linked with right-hemisphere prefrontal activity [39, 51, 53].”
Neural correlates of heart rate variability during emotion (2009, background): “, 2002), the regulation of anticipatory anxiety (Kalisch et al., 2005) and suppression of negative affect (Phan et al.”
A Social-Neuroscience Perspective on Empathy (2006, background): “Recent fMRI studies have identified a limited number of regions in the anterolateral and medial prefrontal cortices that mediate such function (e.g., Kalisch et al., 2005).”
Psychological Flexibility as a Fundamental Aspect of Health (2010, background): “Other social neuroscience studies provide additional support for the notion that acceptance of and openness to experience, and related emotion regulation processes are bound to executive functioning (DeYoung, Peterson, & Higgins, 2005; Kalisch et al., 2005; Ochsner & Gross, 2008).”
Amygdala and Ventromedial Prefrontal Cortex Are Inversely Coupled during Regulation of Negative Affect and Predict the Diurnal Pattern of Cortisol Secretion among Older Adults (2006, positive): “Previous work in younger samples indicates that deliberately diminishing negative affective responses yields increased activation in lateral and dorsal regions of prefrontal cortex (PFC) and/or decreased activation in the amygdala (Beauregard et al., 2001; Ochsner et al., 2002, 2004; Schaefer et al.”
A meta-analysis of instructed fear studies: Implications for conscious appraisal of threat (2010, background): “, 2003) and occur contralateral to the side of electric shock application (where shock is used as UCS) (Kalisch et al. 2005), we have suggested that the region may subserve a primary schematic and stimulus-driven form of conscious awareness of the emotional meaning of a stimulus (“this is bad”, “I d”
The Common Neural Basis of Exerting Self-Control in Multiple Domains (2009, neutral): “…OFC when suppressing as compared to maintaining negative emotions as varied as anxiety resulting from the anticipation of shocks, sadness , and viewing aversive images (Harenski & Hamann, 2006; Kalisch et al., 2005; Kim & Hamann, 2007; Levesque et al., 2003; Ochsner, 2004; Phan et al., 2005).”
Human Empathy Through the Lens of Social Neuroscience (2006, background): “For instance, participants instructed to imagine being in a safe, comfortable place showed reduced behavioral and physiological markers of anxiety related to the anticipation of painful stimulation[82].”
The Neural Substrate of Human Empathy: Effects of Perspective-taking and Cognitive Appraisal (2007, background): “…by denial of relevance (i.e., taking a detached observer position), by implicitly or explicitly generating an image of the observing self which is unaffected by the target, is known to reduce the subjective experience of anxiety, sympathetic arousal, and pain reactivity (Kalisch et al., 2005).”