From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels.

By William A. Catterall. Neuron, 2000

2,118 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/3987523fbc0b9f7e6f3972bf000830f7dffd9703

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In Cellular and Molecular Neuroscience

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Citations in the corpus

Prediction of the human membrane proteome (2010, background): “There are examples of well-studied proteins with many TM segments, including the voltage-gated sodium channels with up to 24 TM segments [40].”
Nav1.1 Localizes to Axons of Parvalbumin-Positive Inhibitory Interneurons: A Circuit Basis for Epileptic Seizures in Mice Carrying an Scn1a Gene Mutation (2007, background): “These channels are heteromultimeric protein complexes consisting of one and one or two subunits (Catterall, 2000).”
Sodium Channel β4, a New Disulfide-Linked Auxiliary Subunit with Similarity to β2 (2003, background): “Possible functions of 4 in sodium channel localization and cell adhesion Sodium channel 1– 3 subunits have been proposed to have important functions in sodium channel localization and cell adhesion (Isom et al., 1995; Catterall, 2000; Ratcliffe et al., 2000; Isom, 2002).”
Compartmentalizing the neuronal plasma membrane from axon initial segments to synapses. (2009, background): “Voltage-Gated sodium channels The most important feature of the AIS and the node is the presence of voltage-gated sodium channels (Catterall, 2000; Isom, 2001).”
Pain: Moving from Symptom Control toward Mechanism-Specific Pharmacologic Management (2004, background): “All of the currently available sodium-channel blockers have a poor therapeutic index because they are nonselective, acting on sodium channels in the peripheral and central nervous systems and cardiovascular system (19).”
Voltage-gated ion channels and gating modifier toxins. (2007, background): “The Ca 3 subfamily of calcium channels (Ca 3.1 to Ca 3.3) conduct1992 Dunlap et al., 1995 Catterall, 2000b Olivera et al., 1994 V V V T-type calcium currents that are important for repetitive action potential firing of neurons in the brain and in the pacemaker cells of the sino-atrial node in the…”
International Union of Pharmacology. XLVII. Nomenclature and Structure-Function Relationships of Voltage-Gated Sodium Channels (2005, background): “-conotoxin (Fozzard and Hanck, 1996; Terlau and Stu¨hmer, 1998; Catterall, 2000).”