Hyperinsulinemia and risk of Alzheimer disease
By José A. Luchsinger, M. Tang, S. Shea, Richard P. Mayeux. Neurology, 2004
663 citations recorded by the source corpus.
Subfields: Physiology, Psychiatry and Mental health, Public Health, Environmental and Occupational Health
View Paper: https://www.semanticscholar.org/paper/37f0c14f4a8aaffa483c4a55c3e4c2782e96a122
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Citations in the corpus
- Epidemiology of Alzheimer Disease (2012, neutral): “The presence of type II diabetes is associated with a approximately twofold increased risk of AD (risk ratios vary between 1.5 and 4.0; Luchsinger et al. 2001; Peila et al. 2002; Farris et al. 2003; Luchsinger et al. 2004a).”
- The Gut Microbiota and Alzheimer’s Disease (2017, neutral): “Insulin resistance and hyperinsulinemia trigger inflammation and are associated with the increased expression of inflammatory agents that contribute to the onset of AD [132, 133] (for review, see [132]).”
- Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation. (2005, background): “The relationship between diabetes, cognitive decline, and Alzheimer’s disease is still under active investigation, but some studies suggest that diabetes may be associated with an increased risk of developing Alzheimer’s disease, along with enhanced decline in some cognitive systems (Arvanitakis et ”
- Alzheimer’s Disease and the β-Amyloid Peptide (2010, neutral): “Thus, insulin acts as an effective inhibitor of the IDE-dependent cleavage of Aβ, which may form the basis for a link between type II diabetes, hyperinsulinemia, and AD [58,59].”