Obesity, cigarette smoking, and telomere length in women.

By A. Valdes, T. Andrew, J. P. Gardner, M. Kimura, E. Oelsner, Lynn Cherkas, A. Aviv, T. Spector. The Lancet, 2005

1,308 citations recorded by the source corpus.

Subfields: Aging, Pediatrics, Perinatology and Child Health, Physiology

View Paper: https://www.semanticscholar.org/paper/371c6cc4f64c3067c06375b8cf6108744500f5ed

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Aging

1. M. Blasco
2. Steve Horvath
3. N. Marchetto
4. M. Haussmann

In Pediatrics, Perinatology and Child Health

1. Steve Horvath
2. Robin M. Murray

In Physiology

1. M. Blasco
2. Steve Horvath
3. N. Marchetto
4. M. Haussmann
5. Manolis Kellis
6. Jason Ernst

Citations in the corpus

• Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates (2012, neutral): “, 1990) that has been shown to have an accelerated rate of decay under environmental stress (Epel et al., 2004; Valdes et al., 2005).”
• Obesity accelerates epigenetic aging of human liver (2014, background): “Cancer Epidemiol Biomarkers Prev 18(3):816–820.”
• Sequence variants at the TERT- CLPTM1L locus associate with many cancer types (2009, neutral): “Although telomere length is partly inherited 30 various environmental factors such as smoking and radiation also affect telomere length 28 .”
• Telomeres: Linking stress and survival, ecology and evolution (2010, background): “Furthermore, short telomeres are a risk factor in cardiovascular disease (Samani et al., 2001), liver cirrhosis (Mason et al., 2005), pulmonary fibrosis (Armanios et al., 2007), diabetes (Valdes et al., 2005), stroke (Martin-Ruiz et al., 2006), and Alzheimer’s disease (Honig et al., 2006).”
• Cellular senescence in cancer and aging. (2007, neutral): “Regarding the impairment of stem cell function, a connection between p16INK4a and stem cell biology has long been suspected based on the analysis of mice deficient in Polycomb genes (Valk-Lingbeek et al., 2004).”
• Mechanisms of DNA damage, repair and mutagenesis (2017, neutral): “Likewise, white blood cells of obese women harbor shorter telomeres than lean women [Valdes et al., 2005].”
• The epigenetic regulation of mammalian telomeres (2007, background): “Finally, a number of environmental factors (such as smoking, obesity and stress) have been shown to accelerate the rate of telomere shortening, and might therefore also have an impact on chromatin modifications at telomeres and the expression of subtelomeric gene”
• Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population (2012, methodology): “Phenotype data used in the current study were previously described in the Twins UK sample for the majority of phenotypes, specifically for telomere length [39,40], blood pressure [41], lung function [42], grip strength [43], BMD [43,44,45], DHEAS [46], serum cholesterol [47,48], serum albumin [49] a”