Fungal secondary metabolites - strategies to activate silent gene clusters.

By Axel A. Brakhage, V. Schroeckh. Fungal Genetics and Biology, 2011

699 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

The rhizosphere microbiome: significance of plant beneficial, plant pathogenic, and human pathogenic microorganisms. (2013, background): “Also, rhizosphere fungi are prolific producers of antibiotic metabolites (Hoffmeister & Keller, 2007; Brakhage & Schroeckh, 2011).”
Bacterial-Fungal Interactions: Hyphens between Agricultural, Clinical, Environmental, and Food Microbiologists (2011, background): “As well as the identification of secondary metabolites, recent findings suggest that BFIs can also be used to activate putative fungal secondary metabolite gene clusters that are not expressed under other culture conditions (50).”
Trichoderma spp. – application and prospects for use in organic farming and industry (2014, background): “Brakhage and Schroeckh (2011) suggested some strategies to activate silent gene clusters by cultivating fungi in conditions that simulate competition and allow the usual biosynthetic pathways to be initiated.”