Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease.

By E. Lakatta, Daniel Levy. Circulation, 2003

2,298 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine

View Paper: https://www.semanticscholar.org/paper/35075edd047b60bfe4682a3d30fdfaef22425b34

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In Cardiology and Cardiovascular Medicine

1. I. Wilkinson
2. James B. Strait
3. J. Cockcroft
4. S. Laurent
5. Michael F. O'Rourke
6. J. Hashimoto
7. E. Lakatta

Citations in the corpus

• Aging Biology and Geriatric Clinical Pharmacology (2004, background): “…vascular control mechanisms including intramural autonomic nerve transmitters, autacoid mediators, smooth muscle receptor, and novel ionic channel mechanisms linked directly to altered endothelial and vessel wall functions (Phillips et al., 1998; Andrawis et al., 2000; Lakatta and Levy, 2003).”
• Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk: a consensus statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task Force. Endorsed by the Society for Vascular Medicine. (2008, background): “It represents subclinical vascular disease, the pathophysiologic substrate that explains why CIMT is a risk factor and a marker of CVD risk.(56,57)”
• Expert consensus document on arterial stiffness: methodological issues and clinical applications. (2006, background): “Indeed, aortic stiffening accompanying age and CV risk factors is caused by various phenomena, including breaks in elastin fibers, accumulation of collagen, fibrosis, inflammation, medial smooth muscle necrosis, calcifications, and diffusion of macromolecules within the arterial wall.(24,65,102) All”
• Exercise and Physical Activity for Older Adults (2020, neutral): “The impact of physical activity on primary aging processes is difficult to study in humans because cellular aging processes and disease mechanisms are highly intertwined (137).”
• Sensitivity of Physiological Measures for Detecting Systematic Variations in Cognitive Demand From a Working Memory Task (2012, background): “…heart rate all decrease with age (Anderson & McNeilly, 1991; Palantini et al., 2006; Porges & Fox, 1986), although a careful reading of the literature suggests that only the assertion that there is a decrease in maximal heart rate with age has been definitively established (Lakatta & Levy, 2003).”
• Towards Ubiquitous Blood Pressure Monitoring via Pulse Transit Time: Theory and Practice (2015, neutral): “We similarly hypothesized the model from reviews [24], [25], in vitro animal studies [32], [34], an in vivo animal study [35], an in vitro human study [36], and an in vivo human study [33].”
• Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation. (2005, background): “The aging heart is susceptible to glycation processes; consequences of which may include various degrees of ventricular dysfunction, such as increased ventricular and vascular stiffness, and altered regulation of vascular tone (Lakatta and Levy, 2003).”
• Mechanical factors in arterial aging: a clinical perspective. (2007, background): “hile this increases with age (4,6), the extent of change is idden since the brachial pulse in youth is markedly mplified, whereas amplification is far less at 80 years of age Fig.”
• Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending lifespan (2008, neutral): “Aortic dysfunction and stiffening occur with increased age in humans (Lakatta and Levy, 2003; Vaitkevicius et al., 1993), and it has been suggested that resveratrol might be protective against these effects (Labinskyy et al.”
• Aging-associated cardiovascular changes and their relationship to heart failure (2012, background): “Human and animal studies have revealed that aging is associated with a reduction in endothelialdependent vasodilatation, thought secondary to reduced NO bioavailability.(49) A number of animal studies have found that NO production and NO levels(52) decline with aging, likely as a result of a decline”
• The impact of a naturalistic hands-free cellular phone task on heart rate and simulated driving performance in two age groups (2011, background): “While heart rate values obtained during maximum exercise clearly decline with age (Lakatta & Levy, 2003), the data on expectations for resting heart rate values are not as consistent.”